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Job DescriptionP07948
Confidence100.00%DateFri May 25 10:07:35 BST 2012
Rank194Aligned Residues234
% Identity23%Templatec3db8A_
PDB info PDB header:transferaseChain: A: PDB Molecule:polo-like kinase 1; PDBTitle: crystal structure of an activated (thr->asp) polo-like2 kinase 1 (plk1) catalytic domain in complex with compound3 041
Resolution3.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   245....250.........260....... ..270........ .280.........290.........300.........310.........
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Query Sequence  ESIKLVKRLGAGQFGEVWMGYYN. NSTKVAVKTLK. . . . PGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTREEPIYIIT
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Template Sequence  KRYMRGRFLGKGGFAKCYEITDMDTKEVFAGKVVPKSMLLKPHQKEKMSTEIAIHKSLDNPHVVGFHGFFEDDDFVYVVL
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   37..40.........50.........60.........70.........80.........90.........100.........110......
 
   320.........330.........340.........350.........360.........370.........380.........390.........
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Query Sequence  EYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTA
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Template Sequence  EICRRRSLLELHKRR. . KAVTEPEARYFMRQTIQGVQYLHNNRVIHRDLKLGNLFLNDDMDVKIGDFGLATKI. . . . . . .
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   117..120.........130. ........140.........150.........160.........170.........180.......
 
   400.........410.........420.........430.........440.........450.........460.........470.........
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Query Sequence  REGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDELYDIMKMC
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Template Sequence  . . . . . . . . . . . . . . . . . . . . HSFEVDIWSLGCILYTLLV. GKPPFETSCLKETYIRIKKNE. YSVPRHINPVASALIRRM
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   214.....220.........230.. .......240.........250... ......260.........270.
 
   480.........490.........500.........510.
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Query Sequence  WKEKAEERPTFDYLQSVLDDFYTATEGQYQQQ
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Template Sequence  LHADPTLRPSVAELLT. . DEFFTSGYAPMRLP
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   272.......280....... ..290.........300.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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