Job Description P07948 Confidence 100.00% Date Fri May 25 10:07:35 BST 2012 Rank 71 Aligned Residues 252 % Identity 37% Template c3d4qA_ PDB info PDB header:transferase Chain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase Resolution 2.80 Å

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		238	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.				.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.
Predicted Secondary structure																																																		.	.	.
Query SS confidence																																																		.	.	.
Query Sequence		D	A	W	E	I	P	R	E	S	I	K	L	V	K	R	L	G	A	G	Q	F	G	E	V	W	M	G	Y	Y	N	N	S	T	K	V	A	V	K	T	L	K	P	G	T	M	S	V	Q	.	.	.	A	F	L	E	E	A	N	L	M	K	T	L	Q	H	D	K	L	V	R	L	Y	A	V	V	T	R	E	E	P
Query Conservation																																																		.	.	.
Alig confidence																																		.	.															.	.	.																							.
Template Conservation																																		.	.																																								.
Template Sequence		D	D	W	E	I	P	D	G	Q	I	T	V	G	Q	R	I	G	S	G	S	F	G	T	V	Y	K	G	K	W	H	G	D	.	.	V	A	V	K	M	L	N	V	T	A	P	T	P	Q	Q	L	Q	A	F	K	N	E	V	G	V	L	R	K	T	R	H	V	N	I	L	L	F	M	G	.	Y	S	T	K	P	Q
Template Known Secondary structure					B			T	T												T	T								S	S	S		.	.								S	S	S																	T	T				T	T	B						.				S	S	S
Template Predicted Secondary structure																																		.	.																																								.
Template SS confidence
		448	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.			480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.		.	520	.	.	.	.
		315	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	Y	I	I	T	E	Y	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	G	K	V	L	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	Y	I	E	R	K	N	Y	I	H	R	D	L	R	A	A	N	V	L	V	S	E	S	L	M	C	K	I	A	D	F	G	L	A	R	V	I	E	D
Query Conservation
Alig confidence																				.																																																												.	.
Template Conservation																				.																																																												.	.
Template Sequence		L	A	I	V	T	Q	W	C	E	G	S	S	L	Y	H	H	L	H	.	I	I	E	T	K	F	E	M	I	K	L	I	D	I	A	R	Q	T	A	Q	G	M	D	Y	L	H	A	K	S	I	I	H	R	D	L	K	S	N	N	I	F	L	H	E	D	L	T	V	K	I	G	D	F	G	L	A	T	V	L	.	.
Template Known Secondary structure										S	S		B							.	T	S																										T	T		B		S			S	G	G	G					T	T	T								T	T		B			.	.
Template Predicted Secondary structure																				.																																																												.	.
Template SS confidence
		525	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.		.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.
		395	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.				420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.		.	.	.	.	.	.	.	.	460	.	.	.					.	.	.
Predicted Secondary structure																											.	.	.																																	.													.	.	.	.
Query SS confidence																											.	.	.																																	.													.	.	.	.
Query Sequence		N	E	Y	T	A	R	E	G	A	K	F	P	I	K	W	T	A	P	E	A	I	N	F	G	C	.	.	.	F	T	I	K	S	D	V	W	S	F	G	I	L	L	Y	E	I	V	T	Y	G	K	I	P	Y	P	G	R	T	N	A	D	.	V	M	T	A	L	S	Q	G	Y	R	M	P	.	.	.	.	R	V	E
Query Conservation																											.	.	.																																	.													.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.																	.	.	.																				.													.													.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.																																							.
Template Sequence		.	.	.	.	.	.	.	.	.	S	G	S	I	L	W	M	A	P	E	V	I	R	M	Q	D	K	N	P	Y	S	F	Q	S	D	V	Y	A	F	G	I	V	L	Y	E	L	M	T	.	G	Q	L	P	Y	S	N	I	N	N	R	D	Q	I	I	F	M	V	G	R	G	Y	L	S	P	D	L	S	K	V	R	S
Template Known Secondary structure		.	.	.	.	.	.	.	.	.					T	T							T	T		S	S				S																		.	S	S		T	T	T	T														T	S					G	G	G	S		T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.																																							.
Template SS confidence
											614	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.		.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.
		467	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	C	P	D	E	L	Y	D	I	M	K	M	C	W	K	E	K	A	E	E	R	P	T	F	D	Y	L	Q	S	V	L	D	D	F	Y	T	A	T	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		N	C	P	K	A	M	K	R	L	M	A	E	C	L	K	K	K	R	D	E	R	P	L	F	P	Q	I	L	A	S	I	E	L	L	A	R	S	L	P
Template Known Secondary structure		T	S												T		S	S	G	G	G	S																T
Template Predicted Secondary structure
Template SS confidence
		684	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions