|   |   |
241 | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | |
|
. | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 310 | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . | . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | I | P | R | E | S | I | K | L | V | K | R | L | G | A | G | Q | F | G | E | V | W | M | G | Y | Y | N | . |
. |
N | S | T | K | V | A | V | K | T | L | K | P | G | T | M | S | V | Q | A | F | L | E | E | A | N | L | M | K | T | L | Q | H | D | K | . |
. |
. |
. |
. |
. |
L | V | R | L | Y | A | V | V | T | R | E |
| Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . | . |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
| . | . | . | . | . | . |
|
|   |
|   |
|   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
D | W | L | Q | E | R | Y | E | I | V | G | N | L | G | E | G | T | F | G | K | V | V | E | C | L | D | H | A | R | G | K | S | Q | V | A | L | K | I | I | R | N | V | G | K | Y | R | E | A | A | R | L | E | I | N | V | L | K | K | I | K | E | K | D | K | E | N | K | F | L | C | V | L | M | S | D | W | F | N | F | H |
| Template Known Secondary structure |   |
|  |  | T | T | T |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | T | T | T | T |  |  |  |  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|
| S |
| B |
|
|  |  |  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
313 | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | |
|
|
|
|
|
|
|
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
| Query Sequence |   |
E | P | I | Y | I | I | T | E | Y | M | A | K | G | S | L | L | D | F | L | K | S | D | E | G | G | K | V | L | L | P | K | L | I | D | F | S | A | Q | I | A | E | G | M | A | Y | I | E | R | K | N | Y | I | H | R | D | L | R | A | A | N | V | L | V | S | E | S | L | M | C | K | I | A | . |
. |
. |
. |
. |
. |
. |
. |
| Query Conservation |   |
  |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |
|
|
|   |   |   |
|
|
|   |
|
|   |   |   |
|
|
|
|   |   |   |   |   |   |
|
|   | . | . | . | . | . | . | . | . |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |
|
|
|
|
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
G | H | M | C | I | A | F | E | L | L | . |
G | K | N | T | F | E | F | L | K | E | N | N | F | Q | P | Y | P | L | P | H | V | R | H | M | A | Y | Q | L | C | H | A | L | R | F | L | H | E | N | Q | L | T | H | T | D | L | K | P | E | N | I | L | F | V | N | S | E | F | E | T | L | Y | N | E | H | K | S | C | E | E |
| Template Known Secondary structure |   |
T |  |  |  |  |  |  |  |
|
| . |
|
| B |  |  |  |  |  |  |  | T | T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
|
|
|
|
| G | G | G |  |  |  | S |
|
|
|  |  |  |  |  |  | T | T | T | T |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
230 | . | . | . | . | . | . | . | . | . | |
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . |
|   |
|   |   |
|
|
|
|
|
|
|
|
|
|
|
385 | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . |
| Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
| Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | F | G | L | A | R | V | I | E | D | N | E | Y | T | A | R | E | G | A | K | F | P | I | K | W | T | A | P | E | A | I | N | F | G | C | F | T | I | K | S | D | V | W | S | F | G | I | L | L | Y | E | I | V | T | Y | G | K | I | P | Y | P | G | R | T | N | A | D | V | M |
| Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
K | S | V | K | N | T | S | I | R | V | A | D | F | G | S | A | T | F | D | H | E | H | H | T | T | I | V | A | T | R | H | . |
. |
. |
. |
Y | R | P | P | E | V | I | L | E | L | G | W | A | Q | P | C | D | V | W | S | I | G | C | I | L | F | E | Y | Y | R | . |
G | F | T | L | F | Q | T | H | E | N | R | E | H | L |
| Template Known Secondary structure |   |
 |  |  | S |
|
|
|  |  |  |
|
|
| T | T |
|  |  | T | T | S |
|
|
| S | S |
| S |
| G | G | . | . | . | . | G |
|
|  |  |  |  | T | T |
|
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S |
|
|
| S | S |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
| . | . | . | . |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
|  |  |
|
|
|
|
|
|  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
309 | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | |
|
|
|
340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | |
370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . |
|   |
|   |   |
454 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 |
| Predicted Secondary structure |   |
 |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |
| Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
T | A | L | S | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | Y | R | M | P | R | V | E | N | C | P | D | E | L | Y | D | I | M | K | M | C | W | K | E | K | A | E | E | R | P | T | F |
| Query Conservation |   |
  |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|
|   |
| Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |
| Template Sequence |   |
V | M | M | E | K | I | L | G | P | I | P | S | H | M | I | H | R | T | R | K | Q | K | Y | F | Y | K | G | G | L | V | W | D | E | N | S | S | D | G | R | Y | V | K | E | N | C | K | P | L | K | S | Y | M | L | Q | D | S | L | E | H | V | Q | L | F | D | L | M | R | R | M | L | E | F | D | P | A | Q | R | I | T | L |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
| S |
| G | G | G |  |  | T | T |  |  |
|
|
| T | T | S |  |  |  |  |  |  |  |  |  |
|
|
| G | G | G | G |
| S |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S | T | T | T | S |
|
|  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
384 | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . |
|   |
|   |   |
491 | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | Y | L | Q | S | V | L | D | D | F | Y | T | A | T | E | G | Q | Y | Q |
| Query Conservation |   |
  |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|
|   | . | . |
|
|   |
|   |   |   |   |   |   |   |   |
| Template Sequence |   |
A | E | A | L | L | . |
. |
H | P | F | F | A | G | L | T | P | E | E | R |
| Template Known Secondary structure |   |
 |  |  |  | T | . | . | S | G | G | G | G | G | S |
|  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |
| . | . |
|  |  |  |
|
|
|
|  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
464 | . | . | . | . | |
|
. | 470 | . | . | . | . | . | . | . | . | . | 480 |
|   |