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Job DescriptionP07948
Confidence100.00%DateFri May 25 10:07:35 BST 2012
Rank7Aligned Residues369
% Identity34%Templatec2ozoA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
Resolution2.60 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   122.......130.........140.........150.........160.........170.........180.........190.........200.
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Query Sequence  NTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRSLDNGGYYISPRITF
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Template Conservation         
 

 


  

  
   
  

 



 
    
   

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Template Sequence  DPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLV. . . . . HDVRFHHFPIERQLNGTYAIAGGKAH
Template Known Secondary structure 
TTSS
TTB
BS

TTT

TT
TTBTT
.....TT
TTS
TTS

B
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   3......10.........20.........30.........40.........50. ........60.........70.......
 
   202.......210.........220.........230.....
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Query Sequence  PCISDMIKHYQKQADGLCRRLEKACISPKPQKPW. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  CGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTA
Template Known Secondary structure  SSTS

TTSSS


SB



TT


B




TTS
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   78.80.........90.........100.........110.........120.........130.........140.........150.......
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
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Template Sequence  HERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVE
Template Known Secondary structure  TTTSTTB
TT

SSS


TT

SSTTTT
TT


TTS
SS
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   158.160.........170.........180.........190.........200.........210.........220.........230.......
 
   236...240.........250.........260.........270 ......
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DKDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNST. . . KVAVKT
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Template Sequence  YLKLKADGLIYCLKEACPNMDTSVFESPFSDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKV
Template Known Secondary structure 

TT
SS


SB






S
SSSSS
S
SS



SB

TTS
SSS
SS
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   238.240.........250.........260.........270.........280.........290.........300.........310.......
 
   277..280.. .......290.........300.........310.........320.........330.........340.........350....
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Query Sequence  LKPGTM. . SVQAFLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEG
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Template Sequence  LKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVC. QAEALMLVMEMAGGGPLHKFLV. GKREEIPVSNVAELLHQVSMG
Template Known Secondary structure 




SSTTTT


TTB

.SSS

TT
BT.T
TTTS
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   371........380.........390.........400..... ....410.........420....... ..430.........440........
 
   355....360.........370.........380.........390.........400.........410.........420.........430....
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Query Sequence  MAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLY
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Template Sequence  MKYLEEKNFVHRNLAARNVLLVNRHYAKISDFGLSKAL. . . . . . . . . . . . GPLKWYAPECINFRKFSSRSDVWSYGVTMW
Template Known Secondary structure  TT


S

SGGGTT


STTTT
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TTS




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   449450.........460.........470.........480...... ...490.........500.........510......
 
   435....440.........450.........460.........470.........480.........490.........500.........
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Query Sequence  EIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQYQ
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Template Conservation 
  
 
  
            
        
   
     

  
    
  

    
   
            
Template Sequence  EALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVE
Template Known Secondary structure  TTS

TTTT

STT





TT

TT
SSTTTS

S
S

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   531........540.........550.........560.........570.........580.........590.........600.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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