|   |   |
289 | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | E | A | N | L | M | K | T | L | Q | H | D | K | L | V | R | L | Y | A | V | V | T | R | E | E | P | I | Y | I | I | T | E | Y | M | A | K | G | S | L | L | D | F | L | K | S | D | E | G | G | K | V | L | L | P | K | L | I | D | F | S | A | Q | I | A | E | G | M | A | Y | I | E | R | K | N | Y | I | H | R | D | L |
| Query Conservation |   |
  |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |
|
|
|   |   |   |
|
|
|   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|   |
|
|   |   |
|   |
|
|
|
|
|   |   | . | . | . | . | . | . | . | . | . |
|   |   |
|   |
|   |   | . |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |
|
|
|   |   |
|
|
|
|   |
|
|
| Template Sequence |   |
L | E | I | N | V | L | K | K | I | K | E | K | F | L | C | V | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
M | S | D | A | F | E | L | L | . |
G | K | N | T | F | E | F | L | K | E | N | N | F | Q | P | Y | P | L | P | H | V | R | H | M | A | Y | Q | L | C | H | A | L | R | F | L | H | E | N | Q | L | T | H | T | D | L |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T |
|
|
| B |
|
| . | . | . | . | . | . | . | . | . | B |
|
|
| B |
|
|
| . |
|
| B |  |  |  |  |  |  | T | T | T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |
|
|
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | 220 | . | . | . | . | |
. | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
369 | 370 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | A | A | N | V | L | V | S | E | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | M | C | K | I | A | D | F | G | L | A | R | V | I | E | D | N | E | Y | T | A | R | E | G | A | K | F | P | I | K | W | T | A | P | E | A | I | N | F | G | C | F | T | I | K | S | D | V | W | S | F | G | I | L | L | Y |
| Query Conservation |   |
  |   |   |
|
|
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|
|   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
| Template Sequence |   |
K | P | E | N | I | L | F | V | N | S | E | F | E | T | L | Y | N | E | E | K | S | V | K | N | T | S | I | R | V | A | D | F | G | S | A | T | F | D | H | E | H | H | T | T | I | V | A | . |
. |
. |
. |
T | R | H | Y | R | P | P | E | V | I | L | E | L | G | W | A | Q | P | C | D | V | W | S | I | G | C | I | L | F |
| Template Known Secondary structure |   |
| G | G | G |  |  |  |  |  |  |  |  |
|
| B |
|
|
| B |
|
|  |  |  |  |  |  |  |  |
|
| G | G | G |
|  |  | T | T | S |
|
|
| S | S |
| S | . | . | . | . |
| G | G | G |
|
|  |  |  |  | T | T |
|
|
| S | T |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
285 | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | |
|
|
|
. | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 |
|   |
|   |   |
435 | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 460 | . | . | . | . | . | . | . | . | . | 470 | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | I | V | T | Y | G | K | I | P | Y | P | G | R | T | N | A | D | V | M | T | A | L | S | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | Y | R | M | P | R | V | E | N | C | P | D | E |
| Query Conservation |   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
E | Y | Y | R | . |
G | F | T | L | F | Q | T | H | E | N | R | E | H | L | V | M | M | E | K | I | L | G | P | I | P | S | H | M | I | H | R | T | R | K | Q | K | Y | F | Y | K | G | G | L | V | W | D | E | N | S | S | D | G | R | Y | V | K | E | N | C | K | P | L | K | S | Y | M | L | Q | D | S | L | E | H | V | Q |
| Template Known Secondary structure |   |
 |  |  |  | . | S | S |
| S |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
| S |
| G | G | G |  |  | T | T |  |  |
|
|
| T | T | S |  |  |  |  |  |  |  |  |  |
|
|
| G | G | G | G |
| S |
|
| S |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
366 | . | . | . | |
370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . |
|   |
|   |   |
472 | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | Y | D | I | M | K | M | C | W | K | E | K | A | E | E | R | P | T | F | D | Y | L | Q | S | V | L | D | D | F | Y | T | A | T | E | G | Q |
| Query Conservation |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|
|
|   |   |   |
|   |   |
|
|   |   |
|   |
|
|   |
|   |
|   | . | . |
|
|
|
|   |   |   |   |   |   |
| Template Sequence |   |
L | F | D | L | M | R | R | M | L | E | F | D | P | A | Q | R | I | T | L | A | E | A | L | L | . |
. |
H | P | F | F | A | G | L | T | P | E |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T |
| S |
| T | T | T | S |
|
|  |  |  |  |  | T | . | . | S | G | G | G | G | G | S |
| S |
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
| . | . |
|
|  |  |
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
445 | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | |
|
. | 470 | . | . | . | . | . | . | . | . |
|   |