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Job DescriptionP07948
Confidence100.00%DateFri May 25 10:07:35 BST 2012
Rank5Aligned Residues431
% Identity75%Templatec2c0iA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   67..70.........80.........90.........100.........110.........120.........130.........140......
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Query Sequence  IVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAKLNTLETEEWFFKDITRKDAERQLLAP
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Template Conservation     
          

    

   

     

          
 

 
 
     
    

 
 


  

  
   
Template Sequence  IVVALYDYEAIHHEDLSFQKGDQMVVLEESGEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAP
Template Known Secondary structure  SS
B


SSSB

B
TT
TTTTT

GGGTTSGGGSTTTT

TST
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   61........70.........80.........90.........100.........110.........120.........130.........140
 
   147..150.........160.........170.........180.........190.........200.........210.........220......
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Query Sequence  GNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKAC
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Template Sequence  GNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPC
Template Known Secondary structure  T

TT

SSSTT
TTTB

STT
SSTTSSSTTSS
SS
SS


SB
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   141........150.........160.........170.........180.........190.........200.........210.........220
 
   227..230.........240.........250.........260.........270.........280.........290.........300......
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Query Sequence  ISPKPQKPWDKDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLY
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Template Sequence  MSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLH
Template Known Secondary structure 









TT
SB

GGGTTTTT


SS
T


TTB

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   221........230.........240.........250.........260.........270.........280.........290.........300
 
   307..310.........320.........330.........340.........350.........360.........370.........380......
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Query Sequence  AVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADF
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Template Conservation 
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Template Sequence  AVV. TKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADF
Template Known Secondary structure  .
SSS


TT
BSTTGGG

TT


S

SGGG
TT



T
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   301.. ......310.........320.........330.........340.........350.........360.........370.........
 
   387..390.........400.........410.........420.........430.........440.........450.........460......
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Query Sequence  GLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVE
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Template Sequence  GLAR. . . . . . . . . . . . . VIPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPE
Template Known Secondary structure  TGGG.............T

GGGS




TTT

SSTT

TT





T
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   380... ......390.........400.........410.........420.........430.........440......
 
   467..470.........480.........490.........500.........510.
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Query Sequence  NCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQYQQQ
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Template Sequence  NCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQEEIP
Template Known Secondary structure  T

T
SSGGGS

TTTS
GGG




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   460.........470.........480.........490.........500....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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