|   |   |
245 | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | |
. | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | S | I | K | L | V | K | R | L | G | A | G | Q | F | G | E | V | W | M | G | Y | Y | N | . |
N | S | T | K | V | A | V | K | T | L | K | P | G | T | M | S | V | Q | . |
. |
. |
. |
. |
. |
. |
A | F | L | E | E | A | N | L | M | K | T | L | Q | H | D | K | L | V | R | L | Y | A | V | V | T | R | E | E | P | I | Y |
| Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |
|
|   |   |   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
N | D | F | S | V | H | R | I | I | G | R | G | G | F | G | E | V | Y | G | C | R | K | A | D | T | G | K | M | Y | A | M | K | C | L | D | K | K | R | I | K | M | K | Q | G | E | T | L | A | L | N | E | R | I | M | L | S | L | V | S | T | G | D | C | P | F | I | V | C | M | S | Y | A | F | H | T | P | D | K | L | S |
| Template Known Secondary structure |   |
G | G |  |  |  |  |  |  |  |  |  |
| S | S | S |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | S |
|
| S | S | B |
|
|  |  |  |  |  |  |  | T | T |  |  |  |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
189 | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . |
|   |
|   |   |
317 | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
I | I | T | E | Y | M | A | K | G | S | L | L | D | F | L | K | S | D | E | G | G | K | V | L | L | P | K | L | I | D | F | S | A | Q | I | A | E | G | M | A | Y | I | E | R | K | N | Y | I | H | R | D | L | R | A | A | N | V | L | V | S | E | S | L | M | C | K | I | A | D | F | G | L | A | R | V | I | E | D | N | E |
| Query Conservation |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |
|
|
|   |   |   |
|
|
|   |
|
|   |   |   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|
|
|   |   |   |
|
|   |
|   |   |   |
|   |   |   | . | . |   |   |
|   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |   |
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |
| Template Sequence |   |
F | I | L | D | L | M | N | G | G | D | L | H | Y | H | L | S | Q | H | . |
. |
G | V | F | S | E | A | D | M | R | F | Y | A | A | E | I | I | L | G | L | E | H | M | H | N | R | F | V | V | Y | R | D | L | K | P | A | N | I | L | L | D | E | H | G | H | V | R | I | S | D | L | G | L | A | C | D | F | S | K | K | K |
| Template Known Secondary structure |   |
 |  |  |  |
|
|
| S |
| B |  |  |  |  |  |  |  |  | . | . |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
|
|
|
|
| G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
|
| T | T |
|  |  |
| S | S |
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
269 | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | |
|
. | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . |
|   |
|   |   |
397 | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | |
420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | |
|
. | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | T | A | R | E | G | A | K | F | P | I | K | W | T | A | P | E | A | I | N | F | G | C | . |
F | T | I | K | S | D | V | W | S | F | G | I | L | L | Y | E | I | V | T | Y | G | K | I | P | Y | P | G | . |
. |
R | T | N | A | D | V | M | T | A | L | S | Q | G | Y | R | M | P | R | V | E | N | C | P | D | E | L | Y |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   | . |   |
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   | . | . |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |
|
|   | . | . | . |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|
|
|
|
|
|   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
| Template Sequence |   |
P | H | A | S | V | G | T | H | . |
. |
. |
G | Y | M | A | P | E | V | L | Q | K | G | V | A | Y | D | S | S | A | D | W | F | S | L | G | C | M | L | F | K | L | L | R | . |
G | H | S | P | F | R | Q | H | K | T | K | D | K | H | E | I | D | R | M | T | L | T | M | A | V | E | L | P | D | S | F | S | P | E | L | R |
| Template Known Secondary structure |   |
|
|
|
|
| S |
| T | . | . | . | T | S |
|
|  |  |  |  | S | S | S |
|
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
| S | S |
| S | S |
| T |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| T | T | S |
|  |  |  |  |
| Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
347 | . | . | 350 | . | . | . | . | |
|
|
. | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | |
. | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . |
|   |
|   |   |
474 | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 490 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |
|
| . | . | . | . | . |
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
| Query Sequence |   |
D | I | M | K | M | C | W | K | E | K | A | E | E | R | P | . |
. |
. |
. |
. |
T | F | D | Y | L | Q | S |
| Query Conservation |   |
  |
|
|   |   |
|   |   |   |   |
|   |   |
|
| . | . | . | . | . |
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |
| Template Sequence |   |
S | L | L | E | G | L | L | Q | R | D | V | N | R | R | L | G | C | L | G | R | G | A | Q | E | V | K | E |
| Template Known Secondary structure |   |
 |  |  |  |  |  |
|
| S | S | S | T | T | S | T | T | T | S | S | S | S |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
423 | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . |
|   |