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Job DescriptionP07948
Confidence100.00%DateFri May 25 10:07:35 BST 2012
Rank1Aligned Residues444
% Identity60%Templatec1y57A_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
Resolution1.91 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   66...70.........80.........90..... ....100.........110.........120.........130.........140....
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Query Sequence  DIVVALYPYDGIHPDDLSFKKGEKMKVLEE. HGEWWKAKSLLTKKEGFIPSNYVAKLNTLETEEWFFKDITRKDAERQLL
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Template Sequence  TTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLL
Template Known Secondary structure  TSS
B


SSSB

B
TT

S

SSSSTTT

GGGTTSGGGSTTS

T
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   84.....90.........100.........110.........120.........130.........140.........150.........160...
 
   145....150.........160.........170.........180.........190.........200.........210.........220....
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Query Sequence  APGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEK
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Template Sequence  NAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTT
Template Known Secondary structure 
TT

TT

SSSTT
TTT
SSS
SSTTSSS

TTSSS



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   164.....170.........180.........190.........200.........210.........220.........230.........240...
 
   225....230...... ...240.........250.........260.........270.........280.........290.........300...
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Query Sequence  ACISPKPQKPWD. KDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLV
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Template Sequence  VCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLV
Template Known Secondary structure  B







SS



TTB

GGGTTTTT
TTSS



TTB
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   244.....250.........260.........270.........280.........290.........300.........310.........320...
 
   304.....310.........320.........330.........340.........350.........360.........370.........380...
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Query Sequence  RLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKI
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Template Sequence  QLYAVVS. EEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKV
Template Known Secondary structure 

.SSS


TTS

TT
S

SGGG
GGG
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   324.....330 .........340.........350.........360.........370.........380.........390.........400..
 
   384.....390.........400.........410.........420.........430.........440.........450.........460...
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Query Sequence  ADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMP
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Template Sequence  ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMP
Template Known Secondary structure 


TT


SS




TTTT
SGGGS




TTS

SSTT

TT



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   403......410.........420.........430.........440.........450.........460.........470.........480..
 
   464.....470.........480.........490.........500.........510
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Query Sequence  RVENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQYQQ
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Template Sequence  CPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQP
Template Known Secondary structure 

TT

T
SSGGGS

TT
TT


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   483......490.........500.........510.........520.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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