Return to main results Retrieve Phyre Job Id

Job DescriptionQ9H3Y6
Confidence100.00%DateSat Jun 16 10:17:08 BST 2012
Rank58Aligned Residues258
% Identity38%Templatec3v5qB_
PDB info PDB header:transferase/transferase inhibitorChain: B: PDB Molecule:nt-3 growth factor receptor; PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   223......230.........240. ........ 250.........260 .........270.........280.........290.........
Predicted Secondary structure 








..



.












Query SS confidence 


















.







.










.






































Query Sequence  WERPHSEFALGRKLGEGYF. GEVWEGLW. LGSLPVAIKVI. KSANMKLTDLAKEIQTLKGLRHERLIRLHAVCSGGEPVY
Query Conservation    
      
   

 
 
.
 
  
  .     



 
.         
  
   
  
 




 
 
         
Alig confidence 


















.







.










.


































..

Template Conservation    
          

 
 
 
 

          



 
             

  
  
 




         ..  
Template Sequence  QHIKRRDIVLKRELGFKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDP. . LI
Template Known Secondary structure 

GGG


S

SSSS

S




TTB




..
Template Predicted Secondary structure 






















..
Template SS confidence 















































































   531........540.........550.........560.........570.........580.........590.........600...... ..
 
   300.........310.........320.........330.........340.........350.........360.........370.........
Predicted Secondary structure 












































Query SS confidence 















































































Query Sequence  IVTELMRKGNLQAFLGTPEGRALRLPPLLGFACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLACKVADFGLARLLKDDI
Query Conservation 

 
    


   
                  


 

 


    





  



      

 




       
Alig confidence 















.






























































Template Conservation 

 
      
     .                                                               
Template Sequence  MVFEYMKHGDLNKFLR. AHGPELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMDVYSTDYY
Template Known Secondary structure 

TT.TT




TT


S

SGGG
GGG







SGGG
B
Template Predicted Secondary structure 











.





































Template SS confidence 















































































   615....620.........630 .........640.........650.........660.........670.........680.........690...
 
   380.........390.........400.........410.........420.........430.........440.........450.........
Predicted Secondary structure 





































Query SS confidence 















































































Query Sequence  YSPSSSSKIPVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHETLQQIMRGYRLPRPAACPAEVYVLM
Query Conservation              
 


 
     
 










 

 
 
  
       

   
  
 
   
   
  
  

Alig confidence 

.....








































































Template Conservation    .....         
           





  





 
               
               
  

Template Sequence  RT. . . . . MLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVM
Template Known Secondary structure 

.....
B
GGG





TTTS

TTTTS
T





TT

Template Predicted Secondary structure 

.....







































Template SS confidence 















































































   711. .......720.........730.........740.........750.........760.........770.........780.....
 
   460.........470.........480........
Predicted Secondary structure 








Query SS confidence 




























Query Sequence  LECWRSSPEERPSFATLREKLHAIHRCHP
Query Conservation    
   

  


   
   
  
    
Alig confidence 




























Template Conservation    

   
  


  


  
       
Template Sequence  LGCWQREPQQRLNIKEIYKILHALGKATP
Template Known Secondary structure 

SSGGGS

T

Template Predicted Secondary structure 










Template SS confidence 




























   804.....810.........820.........830..
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions