|   |   |
226 | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
P | H | S | E | F | A | L | G | R | K | L | G | E | G | Y | F | G | E | V | W | E | G | L | W | L | G | S | L | P | V | A | I | K | V | I | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | A | N | M | K | L | T | D | L | A | K | E | I | Q | T | L | K | G | L |
| Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|
| Template Sequence |   |
R | P | R | T | L | V | R | G | T | V | L | G | Q | E | D | P | Y | A | Y | L | E | A | T | D | E | T | G | E | S | F | E | V | H | V | P | Y | F | T | E | P | P | S | N | A | I | K | Q | M | K | E | E | V | L | R | L | R | L | L | R | G | I | K | N | Q | K | Q | A | K | V | H | L | R | F | I | F | P | F | D | L | V |
| Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| T | T |  |  |  |  |  |  |  |  |  |  | G | G | G | G | S | T | T |
|
| S |  |  |  |  |  |  |  |  |
| B |
|
|
| S |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
262 | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . |
|   |
|   |   |
281 | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | |
. | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | |
|
. | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
| . |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | H | E | R | L | I | R | L | H | A | V | C | S | G | G | E | P | V | Y | I | V | T | E | L | M | . |
R | K | G | N | L | Q | A | F | L | G | T | P | E | G | R | A | . |
. |
L | R | L | P | P | L | L | G | F | A | C | Q | V | A | E | G | M | S | Y | L | E | E | Q | R | V | V | H | R | D | L | A | A | R | N | V | L |
| Query Conservation |   |
  |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |   | . |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |   |
|
|
|
|
|
|   |   |
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |
|
|
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
| Template Sequence |   |
K | D | P | Q | K | K | K | M | I | R | V | M | W | V | L | S | R | F | F | L | Y | P | R | M | Q | S | N | L | Q | T | F | G | E | V | L | L | S | H | S | S | T | H | K | S | L | V | H | H | A | R | L | Q | L | T | L | Q | V | I | R | L | L | A | S | L | H | H | Y | G | L | V | H | T | Y | L | R | P | V | D | I | V |
| Template Known Secondary structure |   |
 |
| T | T | S |
| S |  |  |  |
|
|  |  |  | S |  |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
|
| G | G | G |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
344 | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . |
|   |
|   |   |
358 | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | D | D | G | L | A | C | K | V | A | D | F | G | L | A | R | L | L | K | D | D | I | Y | S | P | S | S | S | S | . |
. |
. |
. |
. |
. |
K | I | P | V | K | W | T | A | P | E | A | A | N | Y | R | V | F | S | Q | K | S | D | V | W | S | F | G | V | L | L | H | E | V | F | T | Y | G | Q | C | P | Y | E | G | M | T |
| Query Conservation |   |
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |
|   |
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |
|
|
|
|
|   | . |
|   |   |
|
|   |   |   |   |
| Template Sequence |   |
L | D | Q | R | G | G | V | F | L | T | G | F | E | H | L | V | R | D | G | A | R | V | V | S | S | V | S | R | G | F | E | P | P | E | L | E | A | R | R | A | T | I | S | Y | H | R | D | R | R | T | L | M | T | F | S | F | D | A | W | A | L | G | L | V | I | Y | W | I | W | C | . |
A | D | L | P | I | G | G | S | E |
| Template Known Secondary structure |   |
 |
| T | T |
|
|  |  |  |
|
| G | G | G |
|  |  | T | T |
|  |  |  |
|
|
|
| T | T |
|
|
|  |  |  |  |  |  |  | T | S | T |  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
|
|
|
|
| S | G |
| Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | |
500 | . | . | . | . | . | . | . | . |
|   |
|   |   |
432 | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
| . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
N | H | E | T | L | Q | Q | I | M | R | G | Y | R | L | P | R | P | A | A | C | P | A | E | V | Y | V | L | M | L | E | C | W | R | S | S | P | E | E | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
P | S | F | A | T | L | R | E | K | L | H | A | I | H | R | C | H |
| Query Conservation |   |
  |   |
|
|   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |
| . | . | . | . | . | . | . | . | . |
|
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
W | I | F | R | S | C | K | N | I | P | Q | P | V | R | A | L | L | E | G | F | L | R | Y | P | K | E | D | R | L | L | P | L | Q | A | M | E | T | P | E | Y | E | Q | L | R | T | E | L | S | A | A | L | P | L | Y |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | G | G | G | S | S |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | T |
| S | S | G | G | G |
|
|
|  |  |  |  |  | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G |
|
| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|
|
|
|
|
|
515 | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . |
|   |