Job Description Q9H3Y6 Confidence 100.00% Date Sat Jun 16 10:17:08 BST 2012 Rank 4 Aligned Residues 427 % Identity 44% Template c2h8hA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor Resolution 2.20 Å

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		56	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	L	A	L	Y	D	F	T	A	R	C	G	G	E	L	S	V	R	R	G	D	R	L	C	A	L	E	E	G	G	G	Y	I	F	A	R	R	L	S	G	Q	P	S	A	G	L	V	P	I	T	H	V	A	K	A	S	P	E	T	L	S	D	Q	P	W	Y	F	S	G	V	S	R	T	Q	A	Q	Q	L	L	L
Query Conservation
Alig confidence																																																									.	.
Template Conservation																																																									.	.
Template Sequence		F	V	A	L	Y	D	Y	E	S	R	T	E	T	D	L	S	F	K	K	G	E	R	L	Q	I	V	N	N	T	E	G	D	W	W	L	A	H	S	L	S	T	G	Q	T	G	Y	I	P	S	N	Y	V	A	P	S	.	.	D	S	I	Q	A	E	E	W	Y	F	G	K	I	T	R	R	E	S	E	R	L	L	L
Template Known Secondary structure					S	S		B				S	S	S	B			B		T	T									S	S	S	S							T	T	T								G	G	G				T	.	.	T	S	G	G	G	S	T	T	B			S											T
Template Predicted Secondary structure																																																									.	.
Template SS confidence
		86	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140			.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.
		136	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.						.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Predicted Secondary structure																													.	.	.	.	.
Query SS confidence																													.	.	.	.	.
Query Sequence		S	P	P	N	E	P	G	A	F	L	I	R	P	S	E	S	S	L	G	G	Y	S	L	S	V	R	A	.	.	.	.	.	Q	A	K	V	C	H	Y	R	V	S	M	A	A	D	G	S	L	Y	L	Q	K	G	R	L	F	P	G	L	E	E	L	L	T	Y	Y	K	A	N	W	K	L	I	Q	N	P	L	L	Q
Query Conservation																													.	.	.	.	.
Alig confidence																													.	.	.	.	.
Template Conservation
Template Sequence		N	A	E	N	P	R	G	T	F	L	V	R	E	S	E	T	T	K	G	A	Y	C	L	S	V	S	D	F	D	N	A	K	G	L	N	V	K	H	Y	K	I	R	K	L	D	S	G	G	F	Y	I	T	S	R	T	Q	F	N	S	L	Q	Q	L	V	A	Y	Y	S	K	H	A	D	G	L	C	H	R	L	T	T
Template Known Secondary structure			T	T			T	T								S	S	S	T	T											T	T	T										B		.			S						T	T				S	S													T	T	S	S	S
Template Predicted Secondary structure
Template SS confidence
		164	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.
		211	.	.	.	.	.	.	.	.					220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.
Predicted Secondary structure											.	.	.	.
Query SS confidence											.	.	.	.
Query Sequence		P	C	M	P	Q	K	A	P	R	.	.	.	.	Q	D	V	W	E	R	P	H	S	E	F	A	L	G	R	K	L	G	E	G	Y	F	G	E	V	W	E	G	L	W	L	G	S	L	P	V	A	I	K	V	I	K	S	A	N	M	K	L	T	D	L	A	K	E	I	Q	T	L	K	G	L	R	H	E	R	L	I
Query Conservation											.	.	.	.
Alig confidence											.	.	.	.
Template Conservation
Template Sequence		V	C	P	T	S	K	P	Q	T	Q	G	L	A	K	D	A	W	E	I	P	R	E	S	L	R	L	E	V	K	L	G	Q	G	C	F	G	E	V	W	M	G	T	W	N	G	T	T	R	V	A	I	K	T	L	K	P	G	T	M	S	P	E	A	F	L	Q	E	A	Q	V	M	K	K	L	R	H	E	K	L	V
Template Known Secondary structure											S	S	S	S	T	T		S	B			G	G	G											S	S									T	T	T										T	T	S	S																		T	T	B
Template Predicted Secondary structure
Template SS confidence
		244	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.
		287	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	L	H	A	V	C	S	G	G	E	P	V	Y	I	V	T	E	L	M	R	K	G	N	L	Q	A	F	L	G	T	P	E	G	R	A	L	R	L	P	P	L	L	G	F	A	C	Q	V	A	E	G	M	S	Y	L	E	E	Q	R	V	V	H	R	D	L	A	A	R	N	V	L	V	D	D	G	L	A	C	K	V
Query Conservation
Alig confidence									.
Template Conservation									.
Template Sequence		Q	L	Y	A	V	V	S	.	E	E	P	I	Y	I	V	T	E	Y	M	S	K	G	S	L	L	D	F	L	K	G	E	T	G	K	Y	L	R	L	P	Q	L	V	D	M	A	A	Q	I	A	S	G	M	A	Y	V	E	R	M	N	Y	V	H	R	D	L	R	A	A	N	I	L	V	G	E	N	L	V	C	K	V
Template Known Secondary structure									.	S	S	S									T	T								S					T	T																							T	T				S			S	G	G	G					G	G	G
Template Predicted Secondary structure									.
Template SS confidence
		324	.	.	.	.	.	330		.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.
		367	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	D	F	G	L	A	R	L	L	K	D	D	I	Y	S	P	S	S	S	S	K	I	P	V	K	W	T	A	P	E	A	A	N	Y	R	V	F	S	Q	K	S	D	V	W	S	F	G	V	L	L	H	E	V	F	T	Y	G	Q	C	P	Y	E	G	M	T	N	H	E	T	L	Q	Q	I	M	R	G	Y	R	L	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	Q	G	A	K	F	P	I	K	W	T	A	P	E	A	A	L	Y	G	R	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	L	T	T	K	G	R	V	P	Y	P	G	M	V	N	R	E	V	L	D	Q	V	E	R	G	Y	R	M	P
Template Known Secondary structure				T	T	S	T	T	T								T	T		S	T	T	S		G	G	G	S																											T	T	T	T			S	S	T	T												T	T
Template Predicted Secondary structure
Template SS confidence
		403	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.
		447	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	P	A	A	C	P	A	E	V	Y	V	L	M	L	E	C	W	R	S	S	P	E	E	R	P	S	F	A	T	L	R	E	K	L	H	A	I	H	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		C	P	P	E	C	P	E	S	L	H	D	L	M	C	Q	C	W	R	K	E	P	E	E	R	P	T	F	E	Y	L	Q	A	F	L	E	D	Y	F	T
Template Known Secondary structure				T	T													T		S	S	G	G	G	S												T	S	S
Template Predicted Secondary structure
Template SS confidence
		483	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.