Return to main results Retrieve Phyre Job Id

Job DescriptionQ9H3Y6
Confidence100.00%DateSat Jun 16 10:17:08 BST 2012
Rank79Aligned Residues250
% Identity36%Templatec1xkkA_
PDB info PDB header:transferaseChain: A: PDB Molecule:epidermal growth factor receptor; PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   225....230.........240......... 250.........260.........270.........280.........290.........300...
Predicted Secondary structure 






.
















Query SS confidence 
























.





















































Query Sequence  RPHSEFALGRKLGEGYFGEVWEGLW. LGSLPVAIKVIKSANMKLTDLAKEIQTLKGLRHERLIRLHAVCSGGEPVYIVTE
Query Conservation 
      
   

 
 

 
  
  .     



 
         
  
   
  
 




 
 
         

 
Alig confidence 
























.












..
































.




Template Conservation 
    
     

 
 

 



        



 
  ..        
   
  
 




           .     
Template Sequence  LKETEFKKIKVLGSGAFGTVYKGLWIPVKIPVAIKELRE. . KANKEILDEAYVMASVDNPHVCRLLGICLTSTV. QLITQ
Template Known Secondary structure 

TTT
SS





..
T


TTB

SSS.
Template Predicted Secondary structure 








..

















.




Template SS confidence 















































































   707..710.........720.........730.........740..... ....750.........760.........770........ .780...
 
   304.....310.........320.........330.........340.........350.........360.........370.........380...
Predicted Secondary structure 













































Query SS confidence 















































































Query Sequence  LMRKGNLQAFLGTPEGRALRLPPLLGFACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLACKVADFGLARLLKDDIYSPS
Query Conservation      


   
                  


 

 


    





  



      

 




           
Alig confidence 











.























































.......



Template Conservation        
     .                     
                                  .......    
Template Sequence  LMPFGCLLDYVR. EHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLA. . . . . . . KLLG
Template Known Secondary structure 

TT
B.TSSS

TT


S


GGGTT


S.......TT
Template Predicted Secondary structure 






.






































.......



Template SS confidence 















































































   792.......800... ......810.........820.........830.........840.........850......... 860...
 
   384.....390.........400.........410.........420.........430.........440.........450.........460...
Predicted Secondary structure 





































Query SS confidence 















































































Query Sequence  SSSKIPVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHETLQQIMRGYRLPRPAACPAEVYVLMLECW
Query Conservation          
 


 
     
 










 

 
 
  
       

   
  
 
   
   
  
  

  
 
Alig confidence 















































































Template Conservation                          

 
 

 



 
   
             
            
  
  

  

Template Sequence  AEEKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCW
Template Known Secondary structure  TT



TTTS




TTS

TTTTS
GGGT





TTB
T
Template Predicted Secondary structure 













































Template SS confidence 















































































   864.....870.........880.........890.........900.........910.........920.........930.........940...
 
   464.....470.........480.....
Predicted Secondary structure 





Query SS confidence 





















Query Sequence  RSSPEERPSFATLREKLHAIHR
Query Conservation    

  


   
   
  
  
Alig confidence 





















Template Conservation    

  


  


  
     
Template Sequence  MIDADSRPKFRELIIEFSKMAR
Template Known Secondary structure 
SSGGGS

Template Predicted Secondary structure 





Template SS confidence 





















   952.......960.........970...
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions