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Job DescriptionQ9H3Y6
Confidence100.00%DateSat Jun 16 10:17:08 BST 2012
Rank3Aligned Residues429
% Identity39%Templatec1oplA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
Resolution3.42 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   52.......60.........70.........80.........90.........100.........110.........120.........130.
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Query Sequence  FPQLFLALYDFTARCGGELSVRRGDRLCALEEGGGYIFARRLSGQPSAGLVPITHVAKASPETLSDQPWYFSGVSRTQAQ
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Template Sequence  DPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT. KNGQGWVPSNYITPVNS. . LEKHSWYHGPVSRNAAE
Template Known Secondary structure 
TTSS
B


STTB

B
TT

TTSS
.SS
GGGSSS..GGGSTT

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   81........90.........100.........110.........120... ......130.........140 .........150.......
 
   132.......140.........150.........160.........170.........180.........190.........200.........210.
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Query Sequence  QLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVCHYRVSMAADGSLYLQKGRLFPGLEELLTYYKANWKLIQNPLLQP
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Template Sequence  YLLS. . SGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYP
Template Known Secondary structure  GG..G

TT
SSSTT
TT

TTS
SSTTS
BSSTT

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   158.160. ........170.........180.........190.........200.........210.........220.........230.....
 
   212.... ...220.........230.........240.........250. ........260.........270.........280...
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Query Sequence  CMPQK. . . . . . . APRQDVWERPHSEFALGRKLGEGYFGEVWEGLWLG. SLPVAIKVIKSANMKLTDLAKEIQTLKGLRHE
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Template Sequence  APKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHP
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SSS
SSSS

B

GGGSGGGTTSSGGGT

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   236...240.........250.........260.........270.........280.........290.........300.........310.....
 
   284.....290.........300.........310.........320.........330.........340.........350.........360...
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Query Sequence  RLIRLHAVCSGGEPVYIVTELMRKGNLQAFLGTPEGRALRLPPLLGFACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLA
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Template Sequence  NLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRNLAARNCLVGENHL
Template Known Secondary structure  TB


SSSS


TT
BS
TTTS
TT
S

SGGG
GGG
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   316...320.........330.........340.........350.........360.........370.........380.........390.....
 
   364.....370.........380.........390.........400.........410.........420.........430.........440...
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Query Sequence  CKVADFGLARLLKDDIYSPSSSSKIPVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHETLQQIMRGY
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Template Sequence  VKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDY
Template Known Secondary structure 

TT


TT



TT



GGG



TTS

SSTT

TTTTT
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   396...400.........410.........420.........430.........440.........450.........460.........470.....
 
   444.....450.........460.........470.........480.....
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Query Sequence  RLPRPAACPAEVYVLMLECWRSSPEERPSFATLREKLHAIHR
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Template Sequence  RMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQ
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TT

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SSGGGS

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   476...480.........490.........500.........510.......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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