Job Description O43639 Confidence 99.91% Date Sat Jun 16 10:26:44 BST 2012 Rank 66 Aligned Residues 177 % Identity 16% Template c1a81E_ PDB info PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam Resolution 3.00 Å

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		198	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.											.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.
Predicted Secondary structure																																																			.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																			.	.	.	.	.	.	.	.	.	.
Query Sequence		H	V	V	Q	T	L	Y	P	F	S	S	V	T	E	E	E	L	N	F	E	K	G	E	T	M	E	V	I	E	K	P	E	N	D	P	E	W	W	K	C	K	N	A	R	G	Q	V	G	L	.	.	.	.	.	.	.	.	.	.	V	P	K	N	Y	V	V	V	L	S	D	G	P	A	L	H	P	A	H	A	P
Query Conservation																																																			.	.	.	.	.	.	.	.	.	.
Alig confidence																																																			.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		G	L	Y	L	L	R	Q	S	R	N	Y	L	G	G	F	A	L	S	V	A	H	G	R	K	A	H	H	Y	T	I	E	R	E	L	N	G	T	Y	A	I	A	G	G	R	T	H	A	S	P	A	D	L	C	H	Y	H	S	Q	E	S	D	G	L	V	C	L	L	K	K	P	F	N	R	P	Q	G	V	Q	P	K
Template Known Secondary structure		T								S	S	S	T	T									S	S	S										T	T	T					T	T	S			B	S	S									T	T			T	T	S	S	S				S	B					T	T
Template Predicted Secondary structure
Template SS confidence
		37	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.
		268	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.		.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.		.	340	.	.	.	.	.
Predicted Secondary structure																																						.																																				.
Query SS confidence																																						.																																				.
Query Sequence		Q	I	S	Y	T	G	P	S	S	S	G	R	F	A	G	R	E	W	Y	Y	G	N	V	T	R	H	Q	A	E	C	A	L	N	E	R	G	.	V	E	G	D	F	L	I	R	D	S	E	S	S	P	S	D	F	S	V	S	L	K	A	S	G	K	N	K	H	F	K	V	Q	L	V	.	D	N	V	Y	C	I	G
Query Conservation																																						.																																				.
Alig confidence																																						.											.																									.
Template Conservation																																																	.
Template Sequence		T	P	Q	L	E	K	L	I	A	T	T	A	H	E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	.	D	N	N	G	S	Y	A	L	C	L	L	H	E	G	K	V	L	H	Y	R	I	D	K	D	K	T	G	K	L	S	I	P
Template Known Secondary structure												T	S	G	G	G		T	T																S	S				T	T								.	S	S	S	S									T	T											T	T	S					T
Template Predicted Secondary structure																																																	.
Template SS confidence
		117	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.		.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.
		346	.		.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380
Predicted Secondary structure				.
Query SS confidence				.
Query Sequence		Q	R	.	R	F	H	T	M	D	E	L	V	E	H	Y	K	K	A	P	I	F	T	S	E	H	G	E	K	L	Y	L	V	R	A	L	Q
Query Conservation				.
Alig confidence				.																		.	.	.	.	.
Template Conservation																						.	.	.	.	.
Template Sequence		E	G	K	K	F	D	T	L	W	Q	L	V	E	H	Y	S	Y	K	A	D	.	.	.	.	.	G	L	L	R	V	L	T	V	P	C	Q
Template Known Secondary structure		T	S			B	S										T	T			T	.	.	.	.	.	T	S	S	S				S	B
Template Predicted Secondary structure																						.	.	.	.	.
Template SS confidence
		230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.						250	.	.	.	.	.	.	.	.	.	260

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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