|   |
1784 | . | . | . | . | . | 1790 | . | . | . | . | . | . | . | . | . | 1800 | . | . | . | . | . | . | . | . | . | 1810 | . | . | . | . | . | . | . | . | . | 1820 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | 1830 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 1840 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | Y | I | L | E | D | F | N | E | A | Q | C | N | T | A | Y | Q | C | L | L | I | A | D | Q | H | C | R | T | R | K | Y | F | L | C | L | A | S | G | I | P | C | V | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
H | V | W | V | H | D | S | C | H | A | . |
. |
. |
. |
. |
. |
N | Q | L | Q | N | Y | R | N | Y | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|
|   |
|
|   |   |   |
|   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|   |   |   |   | . | . |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|
|
|   |   |   |   |   |   |
|
|
|
|   |   |
|
|   |
|
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |
|
|
Template Sequence |   |
G | G | T | T | Q | E | E | M | K | D | A | P | . |
. |
N | A | L | N | T | V | L | L | Q | P | W | H | L | E | K | T | K | K | F | V | E | G | T | W | K | H | E | V | P | K | L | N | I | P | M | G | L | D | W | T | D | E | F | L | M | K | V | S | E | I | S | G | Q | P | I | P | A | S | L | T | K | E | R | G | R | L |
Template Known Secondary structure |   |
|
| B |
|  |  |  |  |  |  | G | G | . | . | G | S | S |  |  |  |  | S | S | G | G | G |
|  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
|
|
|
| S | B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
| . | . |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
274 | . | . | . | . | . | 280 | . | . | . | . | . | |
|
. | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . |
  |
  |   |
1848 | . | 1850 | . | . | . | . | . | . | . | . | . | 1860 | . | . | . | . | . | . | . | . | . | 1870 | . | . | . | . | . | . | . | . | . | 1880 | . | . | . | . | . | . | . | . | . | 1890 | . | . | . | . | . | . | . | . | . | 1900 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | 1910 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | P | A | G | Y | S | L | E | E | Q | R | I | L | D | W | Q | P | R | E | N | P | F | Q | N | L | K | V | L | L | V | S | D | Q | Q | Q | N | F | L | E | L | W | S | E | I | L | M | T | G | G | A | A | S | V | K | Q | H | H | S | S | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
H | N | K | D | I | A | L | G | V | F | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   | . | . | . | . | . | . | . | . |
|   |
|   |   |   |   | . | . | . |
|   |
|
|
|   |
|
|   |
|
|   | . | . |   |   |   |   |   |
|
|   |
|
|   |
|
|
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | D | M | . |
. |
. |
. |
. |
. |
. |
. |
M | T | D | S | H | T | W | . |
. |
. |
L | H | G | K | R | F | A | L | W | G | D | P | . |
. |
D | F | V | M | G | L | V | K | F | L | L | E | L | G | C | E | P | V | H | I | L | C | H | N | G | N | K | R | W | K | K | A | V | D | A | I | L | A | A | S | P | Y | G | K | N |
Template Known Secondary structure |   |
 |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  | . | . | . |  | T | T |
|  |  |  |  |  |
|
|  | . | . |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | S | G | G | G | T | T |
Template Predicted Secondary structure |   |
 |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  | . | . | . |  |
|
|
|  |  |  |  |  |
|
|  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
352 | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 360 | . | |
|
|
. | . | . | . | . | . | . | . | 370 | . | . | . | |
|
. | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . |
  |
  |   |
1919 | 1920 | . | . | . | . | . | . | . | . | . | 1930 | . | . | . | . | . | . | . | . | . | 1940 | . | . | |
|
|
. | . | . | . | . | . | . | 1950 | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 1960 | . | . | . | . | . | . | . | . | . | 1970 | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  | . | . | . |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | V | V | T | D | P | S | C | P | A | S | V | L | K | C | A | E | A | L | Q | L | P | V | V | . |
. |
. |
S | Q | E | W | V | I | Q | C | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
I | V | G | E | R | I | G | F | K | Q | H | P | K | Y | K | H | D | Y | V | S | H |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |
|
|
|
|
|
|
|
|   |   |
|   |
|
|   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|
|   |
|
|
|
|   |
|
|   |   |   |   |   |   |
|   |
Template Sequence |   |
A | T | V | Y | I | G | K | D | L | W | H | L | R | S | L | V | F | T | D | K | P | D | F | M | I | G | N | S | Y | G | K | F | I | Q | R | D | T | L | H | K | G | K | E | F | E | V | P | L | I | R | I | G | F | P | I | F | D | R | H | H | L | H | R | S | T | T |
Template Known Secondary structure |   |
|  |  |  |  | S |
|
|  |  |  |  |  |  |  |  |  |  | S |
|
| S |  |  |  |  |
| T | T |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G |
|
|
|  |  |  |
| S | S |
|
|
| S | S | S | S | G | G | G |
|
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
419 | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . |
  |