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Job DescriptionP51451
Confidence100.00%DateWed May 9 17:30:27 BST 2012
Rank166Aligned Residues249
% Identity26%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   239240.........250.........260.........270.........280.........290.........300.... .....310...
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Query Sequence  QSLRLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKALQHERLVRLYAVVT. . . . . KEPIYIVTE
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Template Sequence  RDITLLECVGKGRYGEVWRGSW. QGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITH
Template Known Secondary structure  TTTT.TT
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   206...210.........220....... ..230.........240.........250.........260.........270.........280....
 
   314.....320.........330.........340.........350...... ...360.........370.........380.....
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Query Sequence  YMARGCLLDFLKTDEGSRLSLPRLIDMSAQIAEGMAYIERMNS. . . . . . . . IHRDLRAANILVSEALCCKIADFGLARII
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Template Conservation                 ...                                                      
       
Template Sequence  YHEMGSLYDYLQLTT. . . LDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMH
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TT
B

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STT
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SGGG
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   285....290......... 300.........310.........320.........330.........340.........350.........360.
 
   386...390.........400.........410. ........420.........430.........440.
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Query Sequence  . . . . DSEYTAQEGAKFPIKWTAPEAIHFGV. . . . . . FTIKADVWSFGVLLMEVVTYGRVPYPGMSN. . . . . . . . . . . . . .
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Template Sequence  SQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPNDPS
Template Known Secondary structure  TTTT








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   362.......370.........380.........390.........400.........410...... ...420.........430.........440
 
   442.......450......... 460.........470.........480.........490...
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Query Sequence  . PEVIRNLERGYRMPRPDT. . . . . . CPPELYRGVIAECWRSRPEERPTFEFLQSVLEDF
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Template Sequence  FEDMRKVVCVDQQRPNIPNRWFSDPTLTSL. AKLMKECWYQNPSARLTALRIKKTLTKI
Template Known Secondary structure  TTS






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   441........450.........460.........470 .........480.........490........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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