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Job DescriptionP51451
Confidence100.00%DateWed May 9 17:30:27 BST 2012
Rank103Aligned Residues242
% Identity40%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   231........240.........250.........260.........270.........280.........290.........300..... ....
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Query Sequence  QDEWEIPRQSLRLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKALQHERLVRLYAVVTK. EPIY
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Template Sequence  YGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIK. . . . . . . EFIEEAKVMMNLSHEKLVQLYGVCTKQRPIF
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GGGB

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TT


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   392.......400.........410.........420.........430... ......440.........450.........460....
 
   310.........320.........330.........340.........350.........360.........370.........380.........
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Query Sequence  IVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQIAEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARIIDSEY
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Template Sequence  IITEYMANGCLLNYLREMRHR. FQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGFP. . . . . . .
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   472.......480.........490.. .......500.........510.........520.........530.........540...
 
   390.........400.........410.........420.........430.........440.........450.........460.........
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Query Sequence  TAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLERGYRMPRPDTCPPELYRGVI
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Template Sequence  . . . . . . . . . VRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKV. YTIM
Template Known Secondary structure  .........GGG





TTS

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   561........570.........580.........590.........600.........610.........620...... ...630
 
   470.........480.........490.......
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Query Sequence  AECWRSRPEERPTFEFLQSVLEDFYTAT
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Template Sequence  YSCWHEKADERPTFKILLSNILDVMDEE
Template Known Secondary structure  TT
SSGGGS


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   631........640.........650........
 
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No model constructed - rank, confidence too low




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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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