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Job DescriptionP51451
Confidence100.00%DateWed May 9 17:30:27 BST 2012
Rank60Aligned Residues252
% Identity34%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   232.......240.........250.........260.........270........ .280.........290.........300........
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Query Sequence  DEWEIPRQSLRLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSP. . . EAFLGEANVMKALQHERLVRLYAVVTKEPI
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Template Sequence  DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD. . VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQL
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   448.450.........460.........470......... 480.........490.........500.........510.........520.....
 
   309310.........320.........330.........340.........350.........360.........370.........380........
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Query Sequence  YIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQIAEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARIIDSE
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Template Sequence  AIVTQWCEGSSLYHHLHII. ETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLA. . . . . .
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   389390.........400.........410. ........420.........430.........440... ......450..... ....460
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Query Sequence  YTAQEGAKFPIKWTAPEAIHFGV. . . FTIKADVWSFGVLLMEVVTYGRVPYPGMSNPE. VIRNLERGYRMP. . . . RPDTC
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Template Sequence  . . . . TVLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNC
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   599600.........610.........620.........630......... 640.........650.........660.........670...
 
   461........470.........480.........490........
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Query Sequence  PPELYRGVIAECWRSRPEERPTFEFLQSVLEDFYTATE
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Template Sequence  PKAM. KRLMAECLKKKRDERPLFPQILASIELLARSLP
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   686... 690.........700.........710.........720..
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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