Job Description P51451 Confidence 100.00% Date Wed May 9 17:30:27 BST 2012 Rank 199 Aligned Residues 272 % Identity 30% Template c3c1xA_ PDB info PDB header:transferase Chain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor Resolution 2.17 Å

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		215	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240			.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.					.	.	.	.	.	270	.	.	.	.	.	.	.			.	.	280	.	.	.	.	.	.
Predicted Secondary structure																												.	.																									.	.	.	.														.	.
Query SS confidence																												.	.																									.	.	.	.														.	.
Query Sequence		R	L	T	L	P	C	V	R	P	A	P	Q	N	P	W	A	Q	D	E	W	E	I	P	R	Q	S	.	.	L	R	L	V	R	K	L	G	S	G	Q	F	G	E	V	W	M	G	Y	Y	K	N	N	M	.	.	.	.	K	V	A	I	K	T	L	K	E	G	T	M	S	.	.	P	E	A	F	L	G	E	A	N
Query Conservation																												.	.																									.	.	.	.														.	.
Alig confidence																												.	.																									.	.	.	.														.	.
Template Conservation
Template Sequence		T	V	H	I	D	L	S	A	L	N	P	E	L	V	Q	A	V	Q	H	V	V	I	G	P	S	S	L	I	V	H	F	N	E	V	I	G	R	G	H	F	G	C	V	Y	H	G	T	L	L	D	N	D	G	K	K	I	H	C	A	V	K	S	L	N	R	I	T	D	I	G	E	V	S	Q	F	L	T	E	G	I
Template Known Secondary structure				S	S			T	T	S							T	T	T	T	T	B			S	T	T													S	S	S										T	T	T												S		S		S											T
Template Predicted Secondary structure
Template SS confidence
		1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.
		287	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.		.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.
Predicted Secondary structure																					.
Query SS confidence																					.
Query Sequence		V	M	K	A	L	Q	H	E	R	L	V	R	L	Y	A	V	V	T	K	.	E	P	I	Y	I	V	T	E	Y	M	A	R	G	C	L	L	D	F	L	K	T	D	E	G	S	R	L	S	L	P	R	L	I	D	M	S	A	Q	I	A	E	G	M	A	Y	I	E	R	M	N	S	I	H	R	D	L	R	A	A	N
Query Conservation																					.
Alig confidence																					.
Template Conservation
Template Sequence		I	M	K	D	F	S	H	P	N	V	L	S	L	L	G	I	C	L	R	S	E	G	S	P	L	V	V	L	P	Y	M	K	H	G	D	L	R	N	F	I	R	N	E	T	H	N	P	T	V	K	D	L	I	G	F	G	L	Q	V	A	K	G	M	K	F	L	A	S	K	K	F	V	H	R	D	L	A	A	R	N
Template Known Secondary structure		T	S	T	T				T	T	B											S	S										T	T		B								T	T				B																					T	T				S				G	G	G
Template Predicted Secondary structure
Template SS confidence
		1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.
		366	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	L	V	S	E	A	L	C	C	K	I	A	D	F	G	L	A	R	I	I	D	S	E	Y	T	A	Q	E	G	A	K	F	P	I	K	W	T	A	P	E	A	I	H	F	G	V	F	T	I	K	A	D	V	W	S	F	G	V	L	L	M	E	V	V	T	Y	G	R	V	P	Y	P	G	M	S	N	P	E	V	I
Query Conservation
Alig confidence																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		C	M	L	D	E	K	F	T	V	K	V	A	D	F	L	P	V	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	K	W	M	A	L	E	S	L	Q	T	Q	K	F	T	T	K	S	D	V	W	S	F	G	V	L	L	W	E	L	M	T	R	G	A	P	P	Y	P	D	V	N	T	F	D	I	T
Template Known Secondary structure						T	T											G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	G	S																												T	T	S			S		T	T	S		S	S
Template Predicted Secondary structure																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.																		.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260	.	.	.	.	.	.	.	.	.	1270	.	.
		446	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	N	L	E	R	G	Y	R	M	P	R	P	D	T	C	P	P	E	L	Y	R	G	V	I	A	E	C	W	R	S	R	P	E	E	R	P	T	F	E	F	L	Q	S	V	L	E	D	F	Y	T	A	T	E	R	Q	Y	E	L	Q
Query Conservation
Alig confidence																					.
Template Conservation																					.
Template Sequence		V	Y	L	L	Q	G	R	R	L	L	Q	P	E	Y	C	P	D	P	L	.	Y	E	V	M	L	K	C	W	H	P	K	A	E	M	R	P	S	F	S	E	L	V	S	R	I	S	A	I	F	S	T	F	I	G	E	H	Y	V	H
Template Known Secondary structure						T	T							T	T						.								T		S	S	G	G	G	S																T			S			B
Template Predicted Secondary structure																					.
Template SS confidence
		1294	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.		.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330	.	.	.	.	.	.	.	.	.	1340	.	.	.	.	.	.	.	.	.	1350	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions