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Job DescriptionP51451
Confidence100.00%DateWed May 9 17:30:27 BST 2012
Rank110Aligned Residues238
% Identity23%Templatec2r7bA_
PDB info PDB header:signaling protein, transferaseChain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   237..240.........250.........260 .........270.. .......280.........290.........300....... ..310
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Query Sequence  PRQSLRLVRKLGSGQFGEVWMGYY. KNNMKVAIKTLK. . . . EGTMSPEAFLGEANVMKALQHERLVRLYAVVTKEP. IYI
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Template Sequence  RPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYF
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   78.80.........90.........100.........110.........120.........130.........140.........150.......
 
   311........320.........330.........340.........350.........360.........370.........380.........390
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Query Sequence  VTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQIAEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARIIDSEYT
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Template Sequence  GLSYAKNGELLKYIRKIGS. . FDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL. . . . .
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   158.160.........170...... ...180.........190.........200.........210.........220.........230
 
   391........400.........410.........420.........430.........440.........450.........460.........470
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Query Sequence  AQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLERGYRMPRPDTCPPELYRGVIA
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Template Sequence  . . . . FVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVA. GLPPFRAGNEYLIFQKIIKLE. YDFPEKFFPKA. RDLVE
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   242.......250.........260.........270....... ..280.........290........ .300......... 310....
 
   471........480........
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Query Sequence  ECWRSRPEERPTFEFLQS
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Template Sequence  KLLVLDATKRLGCEEMEG
Template Known Secondary structure  TTS
SSTTSSTTSGGGTT
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   315....320.........330..
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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