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Job DescriptionP51451
Confidence100.00%DateWed May 9 17:30:27 BST 2012
Rank7Aligned Residues370
% Identity36%Templatec2ozoA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
Resolution2.60 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   116...120.........130.........140.........150.........160.........170.........180.........190.....
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Query Sequence  VESLEMERWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGELIKHYKIRCLDEGGYYISPRITF
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Template Sequence  PDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLV. . . . HDVRFHHFPIERQLNGTYAIAGGKAH
Template Known Secondary structure 

TTSS
TTB
BS

TTT

TT
TTBTT
....TT
TTS
TTS

B
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   2.......10.........20.........30.........40.........50. ........60.........70.......
 
   196...200.........210.........220.........230..
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Query Sequence  PSLQALVQHYSKKGDGLCQRLTLPCVRPAPQNPWAQD. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  CGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTA
Template Known Secondary structure  SSTS

TTSSS


SB



TT


B




TTS
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   78.80.........90.........100.........110.........120.........130.........140.........150.......
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
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Template Sequence  HERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVE
Template Known Secondary structure  TTTSTTB
TT

SSS


TT

SSTTTT
TT


TTS
SS
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   158.160.........170.........180.........190.........200.........210.........220.........230.......
 
   233......240.........250.........260.... .....270
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EWEIPRQSLRLVRKLGSGQFGEVWMGYYKNNM. . . KVAIKT
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Template Sequence  YLKLKADGLIYCLKEACPNMDTSVFESPFSDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKV
Template Known Secondary structure 

TT
SS


SB






S
SSSSS
S
SS



SB

TTS
SSS
SS
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   238.240.........250.........260.........270.........280.........290.........300.........310.......
 
   271..... ...280.........290.........300.........310.........320.........330.........340........
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Query Sequence  LKEGTM. . SPEAFLGEANVMKALQHERLVRLYAVVTKEPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQIAEGM
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Template Sequence  LKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREE. IPVSNVAELLHQVSMGM
Template Known Secondary structure 




SSTTTT


TTB

SSS

TT
BTT
TTT.S
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   371........380.........390.........400.........410.........420.........430.. .......440.........
 
   349350.........360.........370.........380.........390.........400.........410.........420........
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Query Sequence  AYIERMNSIHRDLRAANILVSEALCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEV
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Template Sequence  KYLEEKNFVHRNLAARNVLLVNRHYAKISDFGLSKAL. . . . . . . . . . . GPLKWYAPECINFRKFSSRSDVWSYGVTMWEA
Template Known Secondary structure  TT


S

SGGGTT


STTTT
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TTS




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   450.........460.........470.........480...... ...490.........500.........510........
 
   429430.........440.........450.........460.........470.........480.........490.........500..
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Query Sequence  VTYGRVPYPGMSNPEVIRNLERGYRMPRPDTCPPELYRGVIAECWRSRPEERPTFEFLQSVLEDFYTATERQYE
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Template Conservation   
 
  
            
        
   
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Template Sequence  LSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPEL. YALMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVE
Template Known Secondary structure  TTS

TTTT

STT





TT

.TT
SSTTTS

S
S

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   533......540.........550.........560........ .570.........580.........590.........600.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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