Return to main results Retrieve Phyre Job Id

Job DescriptionP51451
Confidence100.00%DateWed May 9 17:30:27 BST 2012
Rank20Aligned Residues263
% Identity38%Templatec2ivsA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   233......240.........250.........260 .........270.. .......280.........290.........300....
Predicted Secondary structure 












......




..









Query SS confidence 



























. . . . . .











. .































Query Sequence  EWEIPRQSLRLVRKLGSGQFGEVWMGYY. . . . . . KNNMKVAIKTLK. . EGTMSPEAFLGEANVMKALQHERLVRLYAVVT
Query Conservation     
          

 
 

 
     ......     



 
 ..           
   
  
 
 


   
   
Alig confidence 



























......











..































Template Conservation     
          

 
 

 


              



 
              

     
 




       
Template Sequence  KWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACS
Template Known Secondary structure  TTB

GGG
SSSTGGG
SS

TT

TT


TTB


Template Predicted Secondary structure 


































Template SS confidence 















































































   716...720.........730.........740.........750.........760.........770.........780.........790.....
 
   305 ....310.........320......... 330.........340.........350.........360.........370.......
Predicted Secondary structure 
.










......


















Query SS confidence 
.























. . . . . .















































Query Sequence  K. EPIYIVTEYMARGCLLDFLKTDEG. . . . . . SRLSLPRLIDMSAQIAEGMAYIERMNSIHRDLRAANILVSEALCCKIA
Query Conservation   .    

 
    


   
     ......  
          

   
  

    

 


  


       

 
Alig confidence 
.























......















































Template Conservation        

 
    
 
   
                                 
        
    
        

 
Template Sequence  QDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLRALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKIS
Template Known Secondary structure  SSSS


TT
BTTTSTT


TT



SGGGTTT
Template Predicted Secondary structure 














































Template SS confidence 















































































   796...800.........810.........820.........830.........840.........850.........860.........870.....
 
   378.380..... ....390.........400.........410.........420.........430.........440.........450.....
Predicted Secondary structure 





..
































Query SS confidence 







. .





































































Query Sequence  DFGLARII. . DSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLERGYRMP
Query Conservation 




   ..                 


         





 

 
 

 
 
  
            
  
    
Alig confidence 







..





































































Template Conservation 


                         

          






 






 
               
       
Template Sequence  DFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRME
Template Known Secondary structure 

TT

TTTS

SS


S
GGG



TTS

SSTT

GGGTT



Template Predicted Secondary structure 

























































Template SS confidence 















































































   892.......900.........910.........920.........930.........940.........950.........960.........970.
 
   456...460.........470.........480.........490......
Predicted Secondary structure 













Query SS confidence 








































Query Sequence  RPDTCPPELYRGVIAECWRSRPEERPTFEFLQSVLEDFYTA
Query Conservation   
          
   
    
  


   
   

     
Alig confidence 








.






























Template Conservation          
.  

  

  

  


  


  
  
   
Template Sequence  RPDNCSEEM. YRLMLQCWKQEPDKRPVFADISKDLEKMMVK
Template Known Secondary structure 

TT

.T
SSGGGS

T
Template Predicted Secondary structure 





.







Template SS confidence 








































   972.......980 .........990.........1000.........1010.
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions