Job Description P51451 Confidence 100.00% Date Wed May 9 17:30:27 BST 2012 Rank 4 Aligned Residues 430 % Identity 69% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å

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		62	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	V	V	A	L	Y	D	Y	T	A	M	N	D	R	D	L	Q	M	L	K	G	E	K	L	Q	V	L	K	G	T	G	D	W	W	L	A	R	S	L	V	T	G	R	E	G	Y	V	P	S	N	F	V	A	R	V	E	S	L	E	M	E	R	W	F	F	R	S	Q	G	R	K	E	A	E	R	Q	L	L	A	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		I	V	V	A	L	Y	D	Y	E	A	I	H	H	E	D	L	S	F	Q	K	G	D	Q	M	V	V	L	E	E	S	G	E	W	W	K	A	R	S	L	A	T	R	K	E	G	Y	I	P	S	N	Y	V	A	R	V	D	S	L	E	T	E	E	W	F	F	K	G	I	S	R	K	D	A	E	R	Q	L	L	A	P
Template Known Secondary structure						S	S		B				S	S	S	B			B		T	T										T	T							T	T	T								G	G	G				T	T	S	G	G	G	S	T	T			T	T											T	S	T
Template Predicted Secondary structure
Template SS confidence
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
		142	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.		170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220
Predicted Secondary structure																														.
Query SS confidence																														.
Query Sequence		I	N	K	A	G	S	F	L	I	R	E	S	E	T	N	K	G	A	F	S	L	S	V	K	D	V	T	T	.	Q	G	E	L	I	K	H	Y	K	I	R	C	L	D	E	G	G	Y	Y	I	S	P	R	I	T	F	P	S	L	Q	A	L	V	Q	H	Y	S	K	K	G	D	G	L	C	Q	R	L	T	L	P	C
Query Conservation																														.
Alig confidence																														.
Template Conservation
Template Sequence		G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	Y	S	L	S	V	R	D	Y	D	P	R	Q	G	D	T	V	K	H	Y	K	I	R	T	L	D	N	G	G	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L	C	Q	K	L	S	V	P	C
Template Known Secondary structure		T			T	T								S	S	S	T	T											T	T	T										B			S	T	T				S	S	T	T	S			S	S								T	T	S	S		S	S		S	S				S	B
Template Predicted Secondary structure
Template SS confidence
		141	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220
		221	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Predicted Secondary structure
Query SS confidence
Query Sequence		V	R	P	A	P	Q	N	P	W	A	Q	D	E	W	E	I	P	R	Q	S	L	R	L	V	R	K	L	G	S	G	Q	F	G	E	V	W	M	G	Y	Y	K	N	N	M	K	V	A	I	K	T	L	K	E	G	T	M	S	P	E	A	F	L	G	E	A	N	V	M	K	A	L	Q	H	E	R	L	V	R	L	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	S	S	K	P	Q	K	P	W	E	K	D	A	W	E	I	P	R	E	S	L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	K	H	T	K	V	A	V	K	T	M	K	P	G	S	M	S	V	E	A	F	L	A	E	A	N	V	M	K	T	L	Q	H	D	K	L	V	K	L	H
Template Known Secondary structure												T	T		S	B			G	G	G											T	T									T	T	T												S	S														T				T	T	B
Template Predicted Secondary structure
Template SS confidence
		221	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
		301	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380
Predicted Secondary structure
Query SS confidence
Query Sequence		A	V	V	T	K	E	P	I	Y	I	V	T	E	Y	M	A	R	G	C	L	L	D	F	L	K	T	D	E	G	S	R	L	S	L	P	R	L	I	D	M	S	A	Q	I	A	E	G	M	A	Y	I	E	R	M	N	S	I	H	R	D	L	R	A	A	N	I	L	V	S	E	A	L	C	C	K	I	A	D	F	G
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	V	V	T	K	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E	Q	R	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	A	S	L	V	C	K	I	A	D	F	G
Template Known Secondary structure						S	S	S									T	T		B							S	T	T	G	G	G																							T	T				S			S	G	G	G					T	T								T	T
Template Predicted Secondary structure
Template SS confidence
		301	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380
		381	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460
Predicted Secondary structure
Query SS confidence
Query Sequence		L	A	R	I	I	D	S	E	Y	T	A	Q	E	G	A	K	F	P	I	K	W	T	A	P	E	A	I	H	F	G	V	F	T	I	K	A	D	V	W	S	F	G	V	L	L	M	E	V	V	T	Y	G	R	V	P	Y	P	G	M	S	N	P	E	V	I	R	N	L	E	R	G	Y	R	M	P	R	P	D	T	C
Query Conservation
Alig confidence					.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation					.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	A	R	.	.	.	.	.	.	.	.	.	.	.	.	V	I	P	I	K	W	T	A	P	E	A	I	N	F	G	S	F	T	I	K	S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P	E	V	I	R	A	L	E	R	G	Y	R	M	P	R	P	E	N	C
Template Known Secondary structure		G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	T			G	G	G	S																												T	T	T			S	S	T	T												T	T							T	T
Template Predicted Secondary structure					.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		381	.	.													.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.
		461	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	P	E	L	Y	R	G	V	I	A	E	C	W	R	S	R	P	E	E	R	P	T	F	E	F	L	Q	S	V	L	E	D	F	Y	T	A	T	E	R	Q	Y	E	L	Q
Query Conservation
Alig confidence						.
Template Conservation						.
Template Sequence		P	E	E	L	.	Y	N	I	M	M	R	C	W	K	N	R	P	E	E	R	P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A	T	E	S	Q	E	E	I	P
Template Known Secondary structure						.								T		S	S	G	G	G	S												T	T	T	S		G	G	G
Template Predicted Secondary structure						.
Template SS confidence
		462	.	.	.		.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.