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Job DescriptionP51451
Confidence100.00%DateWed May 9 17:30:27 BST 2012
Rank70Aligned Residues260
% Identity34%Templatec1xkkA_
PDB info PDB header:transferaseChain: A: PDB Molecule:epidermal growth factor receptor; PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  IPRQSLRLVRKLGSGQFGEVWMGYY. KNNMKVAIKTLKEGTMSPEAFLGEANVMKALQHERLVRLYAVVTKEPIYIVTEY
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Template Sequence  LKETEFKKIKVLGSGAFGTVYKGLWIPVKIPVAIKELRE. . KANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQL
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   707..710.........720.........730.........740..... ....750.........760.........770.........780....
 
   315....320.........330.........340.........350.........360.........370.........380.........390....
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Query Sequence  MARGCLLDFLKTDEGSRLSLPRLIDMSAQIAEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARIIDSEYTAQEG
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Template Sequence  MPFGCLLDYVREH. KDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLL. . . . . . GAE
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   793......800..... ....810.........820.........830.........840.........850.........860.. ...
 
   395....400.........410.........420.........430.........440.........450.........460.........470....
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Query Sequence  AKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLERGYRMPRPDTCPPELYRGVIAECWR
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Template Sequence  EKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDV. YMIMVKCWM
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   866...870.........880.........890.........900.........910.........920.........930..... ....940....
 
   475....480.........490.........500.....
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Query Sequence  SRPEERPTFEFLQSVLEDFYTATERQYELQP
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Template Sequence  IDADSRPKFRELIIEFSKMARDPQRYLVIQG
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   953......960.........970.........980...
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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