Job Description P51451 Confidence 100.00% Date Wed May 9 17:30:27 BST 2012 Rank 6 Aligned Residues 424 % Identity 39% Template c1k9aB_ PDB info PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution Resolution 2.50 Å

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		55	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.		90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.							.	120	.	.	.	.	.	.	.
Predicted Secondary structure																																					.																														.	.	.	.	.	.
Query SS confidence																																					.																														.	.	.	.	.	.
Query Sequence		H	L	D	E	D	K	H	F	V	V	A	L	Y	D	Y	T	A	M	N	D	R	D	L	Q	M	L	K	G	E	K	L	Q	V	L	K	.	G	T	G	D	W	W	L	A	R	S	L	V	T	G	R	E	G	Y	V	P	S	N	F	V	A	R	V	E	S	.	.	.	.	.	.	L	E	M	E	R	W	F	F	R
Query Conservation																																					.																														.	.	.	.	.	.
Alig confidence																																					.																														.	.	.	.	.	.
Template Conservation
Template Sequence		A	S	W	P	S	G	T	E	C	I	A	K	Y	N	F	H	G	T	A	E	Q	D	L	P	F	C	K	G	D	V	L	T	I	V	A	V	T	K	D	P	N	W	Y	K	A	K	N	K	V	G	R	E	G	I	I	P	A	N	Y	V	Q	K	R	E	G	V	K	A	G	T	K	L	S	L	M	P	W	F	H	G
Template Known Secondary structure		S				T	T						S	S		B			S	S	T	T	B			B		T	T										S	S	T	T							T	T	S							G	G	G										S	S	S			S		T	T	B
Template Predicted Secondary structure
Template SS confidence
		6	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.
		128	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	Q	G	R	K	E	A	E	R	Q	L	L	A	P	I	N	K	A	G	S	F	L	I	R	E	S	E	T	N	K	G	A	F	S	L	S	V	K	D	V	T	T	Q	G	E	L	I	K	H	Y	K	I	R	C	L	D	E	G	G	Y	Y	I	S	P	R	I	T	F	P	S	L	Q	A	L	V	Q	H	Y	S	K
Query Conservation
Alig confidence																.	.																							.	.	.	.													.
Template Conservation																.	.																							.	.	.	.													.
Template Sequence		K	I	T	R	E	Q	A	E	R	L	L	Y	P	P	.	.	E	T	G	L	F	L	V	R	E	S	T	N	Y	P	G	D	Y	T	L	C	V	S	.	.	.	.	C	E	G	K	V	E	H	Y	R	I	M	Y	.	H	A	S	K	L	S	I	D	E	E	V	Y	F	E	N	L	M	Q	L	V	E	H	Y	T	T
Template Known Secondary structure		S										T		S		.	.		T	T								S	S	S	T	T								.	.	.	.		T	T										.		T	T				S	S	S	S	S		B	S	S
Template Predicted Secondary structure																.	.																							.	.	.	.													.
Template SS confidence
		86	.	.	.	90	.	.	.	.	.	.	.	.	.			100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.					.	.	.	.	.	.	.	.	130	.	.	.		.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.
		208	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230				.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.
Predicted Secondary structure																									.	.	.
Query SS confidence																									.	.	.
Query Sequence		K	G	D	G	L	C	Q	R	L	T	L	P	C	V	R	P	A	P	Q	N	P	W	A	.	.	.	Q	D	E	W	E	I	P	R	Q	S	L	R	L	V	R	K	L	G	S	G	Q	F	G	E	V	W	M	G	Y	Y	K	N	N	M	K	V	A	I	K	T	L	K	E	G	T	M	S	P	E	A	F	L	G	E
Query Conservation																									.	.	.
Alig confidence																									.	.	.																																.													.
Template Conservation																																																											.													.
Template Sequence		D	A	D	G	L	C	T	R	L	I	K	P	K	V	M	E	G	T	V	A	A	Q	D	E	F	Y	R	S	G	W	A	L	N	M	K	E	L	K	L	L	Q	T	I	G	K	G	E	F	G	D	V	M	L	G	D	Y	R	.	G	N	K	V	A	V	K	C	I	K	N	D	.	A	T	A	Q	A	F	L	A	E
Template Known Secondary structure				T	T	S	S	S				S	B				S	S											T	T		B			G	G	G											T	T									T	.	T									S	S		.	T	T	S
Template Predicted Secondary structure																																																											.													.
Template SS confidence
		159	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.		.	.	.	.	220	.	.	.	.	.	.	.		.	.	230	.	.	.	.	.	.
		285	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.			.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.
Predicted Secondary structure																									.	.
Query SS confidence																									.	.
Query Sequence		A	N	V	M	K	A	L	Q	H	E	R	L	V	R	L	Y	A	V	V	T	K	E	P	.	.	I	Y	I	V	T	E	Y	M	A	R	G	C	L	L	D	F	L	K	T	D	E	G	S	R	L	S	L	P	R	L	I	D	M	S	A	Q	I	A	E	G	M	A	Y	I	E	R	M	N	S	I	H	R	D	L	R
Query Conservation																									.	.
Alig confidence																									.	.
Template Conservation
Template Sequence		A	S	V	M	T	Q	L	R	H	S	N	L	V	Q	L	L	G	V	I	V	E	E	K	G	G	L	Y	I	V	T	E	Y	M	A	K	G	S	L	V	D	Y	L	R	S	R	G	R	S	V	L	G	G	D	C	L	L	K	F	S	L	D	V	C	E	A	M	E	Y	L	E	G	N	N	F	V	H	R	D	L	A
Template Known Secondary structure						T	T				T	T	B										S	S	S										T	T		B										T	T	T																							T	T		B		S
Template Predicted Secondary structure
Template SS confidence
		237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.
		363	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	A	N	I	L	V	S	E	A	L	C	C	K	I	A	D	F	G	L	A	R	I	I	D	S	E	Y	T	A	Q	E	G	A	K	F	P	I	K	W	T	A	P	E	A	I	H	F	G	V	F	T	I	K	A	D	V	W	S	F	G	V	L	L	M	E	V	V	T	Y	G	R	V	P	Y	P	G	M	S	N	P
Query Conservation
Alig confidence																							.	.	.	.	.	.	.	.	.
Template Conservation																							.	.	.	.	.	.	.	.	.
Template Sequence		A	R	N	V	L	V	S	E	D	N	V	A	K	V	S	D	F	G	L	T	K	.	.	.	.	.	.	.	.	.	E	A	G	K	L	P	V	K	W	T	A	P	E	A	L	R	E	K	K	F	S	T	K	S	D	V	W	S	F	G	I	L	L	W	E	I	Y	S	F	G	R	V	P	Y	P	R	I	P	L	K
Template Known Secondary structure		G	G	G					T	T									T	T		B	.	.	.	.	.	.	.	.	.							T	T	T	S						T	T	T																				T	T	T			S	S	T	T	S		T	T
Template Predicted Secondary structure																							.	.	.	.	.	.	.	.	.
Template SS confidence
		317	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.										.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.
		443	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	V	I	R	N	L	E	R	G	Y	R	M	P	R	P	D	T	C	P	P	E	L	Y	R	G	V	I	A	E	C	W	R	S	R	P	E	E	R	P	T	F	E	F	L	Q	S	V	L	E	D	F	Y	T	A	T
Query Conservation
Alig confidence																								.
Template Conservation																								.
Template Sequence		D	V	V	P	R	V	E	K	G	Y	K	M	D	A	P	D	G	C	P	P	A	V	.	Y	D	V	M	K	N	C	W	H	L	D	A	A	T	R	P	T	F	L	Q	L	R	E	Q	L	E	H	I	R	T	H	E
Template Known Secondary structure		T						T	T	T							T	T						.								T		S	S	G	G	G	S																	T
Template Predicted Secondary structure																								.
Template SS confidence
		394	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.		.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.