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Job DescriptionQ9UKW4
Confidence100.00%DateThu Apr 26 09:47:10 BST 2012
Rank1Aligned Residues539
% Identity63%Templatec3ky9B_
PDB info PDB header:apoptosisChain: B: PDB Molecule:proto-oncogene vav; PDBTitle: autoinhibited vav1
Resolution2.73 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.........30.........40.........50.........60.........70.........80.
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Query Sequence  EPWKQCAQWLIHCKVLPTNHRVTWDSAQVFDLAQTLRDGVLLCQLLNNLRAHSINLKEINLRPQMSQFLCLKNIRTFLTA
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Template Conservation          

     
               
   

 
  

 
 
   
  
        
      
  

  

  
Template Sequence  ELWRQCTHWLIQCRVLPPSHRVTWEGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQFLCLKNIRTFLST
Template Known Secondary structure 
TT
S
TTSTTTSTT

SSTSTTSS
GGGS
SS
TTB
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   2.......10.........20.........30.........40.........50.........60.........70.........80.
 
   82.......90.........100.........110.........120.........130.........140.........150.........160.
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Query Sequence  CCETFGMRKSELFEAFDLFDVRDFGKVIETLSRLSRTPIALATGIRPFPTEESINDEDIYKGLPDLIDETLVEDEEDLYD
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Template Sequence  CCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPIAQNRGIMPFD. . . . . . . EDIYSGLSDQI. . . . . . DDEDLYD
Template Known Secondary structure  TT


TTSS

T
S
STTTGGGT




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GGGG
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TTGGG
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   82.......90.........100.........110.........120.........130 .........140. .......
 
   162....... 170.........180.........190.........200.........210.........220.........230.........240
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Query Sequence  CVYGEDEG. GEVYEDLMKAEEAHQPKCPENDIRSCCLAEIKQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPE
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Template Conservation             
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Template Sequence  CVENEEAEGDEIYEDLM. . . . . . . RSMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFLKPLQRFLKPQDIEIIFINIED
Template Known Secondary structure  GS

TT.......



TTTTTS
TTTS
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   162.......170........ .180.........190.........200.........210.........220.........230....
 
   241........250.........260.........270.........280.........290.........300.........310.........320
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Query Sequence  LVKLHRNLMQEIHDSIVNKNDQNLYQVFINYKERLVIYGQYCSGVESAISSLDYISKTKEDVKLKLEECSKRANNGKFTL
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Template Conservation 
   
  

  

          

 

      
  
  
  
   
   
         
               
 
Template Sequence  LLRVHTHFLKEMKEALGTPGAANLYQVFIKYKERFLVYGRYCSQVESASKHLDRVAAAREDVQMKLEECSQRANNGRFTL
Template Known Secondary structure  SSTT
STTGGGGT
TTTTTTS

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   243......250.........260.........270.........280.........290.........300.........310.........320..
 
   321........330.........340.........350.........360.........370.........380.........390.........400
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Query Sequence  RDLLVVPMQRVLKYHLLLQELVKHTTDPTEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQLSIENLNQPVLLFGR
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Template Sequence  RDLLMVPMQRVLKYHLLLQELVKHTQEAMEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGR
Template Known Secondary structure  T


T

S
GGGG

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   323......330.........340.........350.........360.........370.........380.........390.........400..
 
   401........410.........420.........430.........440.........450.........460.........470.........480
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Query Sequence  PQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKGDNYEMKEIIDLQQYKIANNPTTDKENKKWSYGFYLIHTQGQNGL
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Template Sequence  PKIDGELKIT. . . SVERMDRYAFLLDKALLICKRRGDSYDLKDFVNLHSFQVRDDSSGDRDNKKWSHMFLLIEDQGAQGY
Template Known Secondary structure  ...
S


TTTTGGG

SSTTTT
TT
TTSS
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   403......410.. .......420.........430.........440.........450.........460.........470.........
 
   481........490.........500.........510.........520.........530.........540.........550.........560
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Query Sequence  EFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHDFKMHTFTRVTSCKVCQMLLRGTFYQGYLCFKCGARAHKECLGRVD
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Template Sequence  ELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRASAHKECLGRVP
Template Known Secondary structure  SSS
TTTTGGG



SS

B
TTT
SB

SSS

TTT


SGGGGGS
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   483......490.........500.........510.........520.........530.........540.........550.........560..
 
   561..
Predicted Secondary structure 


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Query Sequence  NCG
Query Conservation     
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Template Conservation     
Template Sequence  PCG
Template Known Secondary structure 


Template Predicted Secondary structure 


Template SS confidence 


   563..
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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