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Job DescriptionP07947
Confidence100.00%DateFri May 25 09:28:30 BST 2012
Rank169Aligned Residues254
% Identity27%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   271........280.........290.........300.........310.........320.........330.........340 .....
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Query Sequence  EIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVS. . . . . EEPIY
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Template Sequence  RTVARDITLLECVGKGRYGEVWRGSW. QGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLW
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TTTTTT.TT
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TT
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   202.......210.........220....... ..230.........240.........250.........260.........270.........280
 
   346...350.........360.........370.........380.........390.. .......400.........410.......
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Query Sequence  IVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNY. . . . . . . . IHRDLRAANILVGENLVCKIADFGL
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Template Sequence  LITHYHEMGSLYDYLQLTT. . . LDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGL
Template Known Secondary structure 

TT
B

...B
S
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STT
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S

SGGG
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TT
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   281........290......... 300.........310.........320.........330.........340.........350.......
 
   418.420.. .......430.........440........ .450.........460.........470........
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Query Sequence  ARLIE. . . DNEYTARQGAKFPIKWTAPEAALYGR. . . . . . FTIKSDVWSFGILQTELVTKGRVPYPGMVN. . . . . . . . . .
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Template Sequence  AVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVP
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   358.360.........370.........380.........390.........400.........410...... ...420.........430......
 
   479480.........490...... ...500.........510.........520.........
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Query Sequence  . . . . . REVLEQVERGYRMPCPQG. . . . . . CPESLHELMNLCWKKDPDERPTFEYIQSFLEDY
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Template Sequence  NDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
Template Known Secondary structure  SS

TTS






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   437..440.........450.........460.........470.........480.........490........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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