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Job DescriptionP07947
Confidence100.00%DateFri May 25 09:28:30 BST 2012
Rank63Aligned Residues262
% Identity32%Templatec3fupB_
PDB info PDB header:transferaseChain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   268.270.........280.........290........ .300.........310. ........320.........330.........340.
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Query Sequence  DAWEIPRESLRLEVKLGQGCFGEVWMGTWNG. . . . . TTKVAIKTLKPGT. MMPEAFLQEAQIMKKLRHDKLVPLYAVVSE
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Template Sequence  DPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCY.
Template Known Secondary structure 
TTGGG
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   840.........850.........860.........870.........880.........890.........900.........910........
 
   342.......350.........360.........370.........380.........390.........400.........410.........420.
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Query Sequence  EPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLI
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Template Sequence  SNLKLIMEYLPYGSLRDYLQKHKER. IDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVL
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TT
BTTTSTTT.

TTT




GGGTT


TT

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   919920.........930.........940... ......950.........960.........970.........980.........990.......
 
   422.......430.........440.........450.........460.........470..... ....480.....
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Query Sequence  EDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPG. . . . . . . . . . . . . . . . MVNREVLEQV
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Template Sequence  PQDKEKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFT. YIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
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TT





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   1002.......1010.........1020.........1030.........1040....... ..1050.........1060.........1070.........1080
 
   486...490.........500.........510.........520.........530..
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Query Sequence  ERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTA
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Template Sequence  KNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDQ
Template Known Secondary structure  TT





TT

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   1083......1090.........1100.........1110.........1120.........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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