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Job DescriptionP07947
Confidence100.00%DateFri May 25 09:28:30 BST 2012
Rank247Aligned Residues261
% Identity25%Templatec2vagA_
PDB info PDB header:transferaseChain: A: PDB Molecule:dual specificity protein kinase clk1; PDBTitle: crystal structure of di-phosphorylated human clk1 in2 complex with a novel substituted indole inhibitor
Resolution1.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   271........280.........290........ .300.........310.........320.........330.. .......340..
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Query Sequence  EIPRESLRLEVKLGQGCFGEVWMGTWNG. . TTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKL. . . . . . VPLYAVVSEE
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Template Sequence  DVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHH
Template Known Secondary structure 
TTTTTTTTTT
SS
TT
TT
B

T
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   155....160.........170.........180.........190.........200.........210.........220.........230....
 
   343......350.........360.........370.........380.........390.........400.........410.........420..
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Query Sequence  PIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIE
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Template Sequence  GHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNKRDERTLI
Template Known Secondary structure  T



BTTT



TT




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   235....240.........250.........260.........270.........280.........290.........300.........310....
 
   423..... .430.........440.........450.........460.........470.........480.......
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Query Sequence  DNEYTA. . . . . . . . . . RQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVER. . . . .
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Template Sequence  NPDIKVVDFGSATYDDEHHSTLVRHYRAPEVILALGWSQPCDVWSIGCILIEYYL. GFTVFPTHDSKEHLAMMERILGPL
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SS
TTS


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S

TTS

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   318.320.........330.........340.........350.........360.........370.. .......380.........390......
 
   488.490.........500.........510.........520.........
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDY
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Template Sequence  PKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRACKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALK. . HPF
Template Known Secondary structure 

S
GGGTT


TTS


GGGG
S

ST
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TT..SGG
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   399400.........410.........420.........430.........440.........450.........460.........470... ...
 
   530....
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Query Sequence  FTATE
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Template Conservation 
  

Template Sequence  FDLLK
Template Known Secondary structure  GGGG
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   477..480.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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