Return to main results Retrieve Phyre Job Id

Job DescriptionP07947
Confidence100.00%DateFri May 25 09:28:30 BST 2012
Rank114Aligned Residues246
% Identity23%Templatec2r7bA_
PDB info PDB header:signaling protein, transferaseChain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   273......280.........290....... ..300........ .310.........320.........330.........340. .....
Predicted Secondary structure 








.



....










.

Query SS confidence 
























.










. . . .
































.




Query Sequence  PRESLRLEVKLGQGCFGEVWMGTWN. GTTKVAIKTLK. . . . PGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSE. EPIYI
Query Conservation            

 
 

 
      .    



   ....           
   
  
 
  

        .     
Alig confidence 
























.










....
































.




Template Conservation      
     

 
 

 

 
     
  



 
                
  

  
 
  

              
Template Sequence  RPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYF
Template Known Secondary structure 
GGG
SS
TTT

TT
T


TTB


SS
Template Predicted Secondary structure 



































Template SS confidence 















































































   78.80.........90.........100.........110.........120.........130.........140.........150.......
 
   347..350.........360.........370.........380.........390.........400.........410.........420......
Predicted Secondary structure 





































Query SS confidence 















































































Query Sequence  VTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEY
Query Conservation 
 
    
 
   
                       
  

     
 


  
 

       
 



         
Alig confidence 
















..























































.....
Template Conservation 
 
      
       ..              
           
 
       
                   .....
Template Sequence  GLSYAKNGELLKYIRKI. . GSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL. . . . .
Template Known Secondary structure 

TT
BS..SS

TT




TTT
TTS



TT

.....
Template Predicted Secondary structure 













..































.....
Template SS confidence 















































































   158.160.........170.... .....180.........190.........200.........210.........220.........230
 
   427..430.........440.........450.........460.........470.........480.........490.........500......
Predicted Secondary structure 


































Query SS confidence 















































































Query Sequence  TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMN
Query Conservation               


           



 
  
 

 
 
  
            
        
   
     

 
Alig confidence  .....



































.




















.















Template Conservation  .....          
      
    





  



 
.
  

           
    .       
    


 
Template Sequence  . . . . . FVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVA. GLPPFRAGNEYLIFQKIIKLE. YDFPEKFFPKARDLVE
Template Known Secondary structure  .....



GGG

SS


.SS
S


SST
.



SSS
Template Predicted Secondary structure  .....






















.











.







Template SS confidence 















































































   242.......250.........260.........270....... ..280.........290........ .300.........310....
 
   507..510.........520.... .....530..
Predicted Secondary structure 






...
Query SS confidence 

















. . .







Query Sequence  LCWKKDPDERPTFEYIQS. . . FLEDYFTA
Query Conservation   
    
  

    
  ... 
      
Alig confidence 

















...







Template Conservation    
  

  
 
  
 
    
  



 
Template Sequence  KLLVLDATKRLGCEEMEGYGPLKAHPFFE
Template Known Secondary structure  TTS
SSTTSSTTSGGGTTSGGGT
Template Predicted Secondary structure 














Template SS confidence 




























   315....320.........330.........340...
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions