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Job DescriptionP07947
Confidence100.00%DateFri May 25 09:28:30 BST 2012
Rank244Aligned Residues249
% Identity23%Templatec2ojiA_
PDB info PDB header:transferaseChain: A: PDB Molecule:mitogen-activated protein kinase 1; PDBTitle: crystal structure of erk2 in complex with n-benzyl-4-(4-(3-2 chlorophenyl)-1h-pyrazol-3-yl)-1h-pyrrole-2-carboxamide
Resolution2.60 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   270.........280.........290....... ..300.........310... ......320.........330.........340.
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Query Sequence  WEIPRESLRLEVKLGQGCFGEVWMGTWN. GTTKVAIKTLKPGTMM. . PEAFLQEAQIMKKLRHDKLVPLYAVVSE. . . . .
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Template Sequence  FDVG. PRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQ
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.SSTTTTTT

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   17..20 .........30.........40.........50.........60.........70.........80.........90.....
 
   342.......350.........360.........370.........380.........390.........400.........410.........420
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Query Sequence  . EPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARL
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Template Sequence  MKDVYIVQDLMETDLYKLLKTQH. . . . LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARV
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   96...100.........110........ .120.........130.........140.........150.........160.........170.
 
   421........430...... ...440.........450.........460.........470.........480.........490....
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Query Sequence  IEDNEYTARQGAKFPI. . . KWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCP. . .
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Template Sequence  ADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS. NRPIFPGKHYLDQLNHILGILGSPSQEDL
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GGG
B

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   172.......180.........190.........200.........210.........220. ........230.........240.........250
 
   495....500.........510.........520....
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . QGCPESLHELMNLCWKKDPDERPTFEYIQS
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Template Sequence  NCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALA
Template Known Secondary structure  S


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   251........260.........270.........280.........290.........300.......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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