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Job DescriptionP07947
Confidence100.00%DateFri May 25 09:28:30 BST 2012
Rank5Aligned Residues431
% Identity66%Templatec2c0iA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   95....100.........110.........120.........130.........140.........150.........160.........170....
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Query Sequence  IFVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLN
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Template Sequence  IVVALYDYEAIHHEDLSFQKGDQMVVLEE. SGEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLA
Template Known Secondary structure  SS
B


SSSB

B
TT
.TTTTT

GGGTTSGGGSTTTT

TS
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   61........70.........80......... 90.........100.........110.........120.........130.........
 
   175....180.........190.........200.........210.........220.........230.........240.........250....
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Query Sequence  PGNQRGIFLVRESETTKGAYSLSIRDWDEIRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTV
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Template Sequence  PGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVP
Template Known Secondary structure  TT

TT

SSSTT
TTTB

STT
SSTTSSSTTSS
SS
SS


SB
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   140.........150.........160.........170.........180.........190.........200.........210.........
 
   255....260.........270.........280.........290.........300.........310.........320.........330....
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Query Sequence  CPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVP
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Template Sequence  CMSSKPQ. KPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVK
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TT
SB

GGGTTTTT


SS
T


TTB

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   220...... ...230.........240.........250.........260.........270.........280.........290........
 
   335....340.........350.........360.........370.........380.........390.........400.........410....
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Query Sequence  LYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIAD
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Template Sequence  LHAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIAD
Template Known Secondary structure 
SSS


TT
BSTTGGG

TT


S

SGGG
TT



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   299300.........310.........320.........330.........340.........350.........360.........370........
 
   415....420.........430.........440.........450.........460.........470.........480.........490....
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Query Sequence  FGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCP
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Template Sequence  FGLAR. . . . . . . . . . . . . VIPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRP
Template Known Secondary structure  TTGGG.............T

GGGS




TTT

SSTT

TT





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   379380... ......390.........400.........410.........420.........430.........440.....
 
   495....500.........510.........520.........530.........540
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Query Sequence  QGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPG
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Template Sequence  ENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQEEIP
Template Known Secondary structure  TT

T
SSGGGS

TTTS
GGG




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   459460.........470.........480.........490.........500....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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