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Job DescriptionP07947
Confidence100.00%DateFri May 25 09:28:30 BST 2012
Rank1Aligned Residues449
% Identity84%Templatec1y57A_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
Resolution1.91 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   95....100.........110.........120.........130.........140.........150.........160.........170....
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Query Sequence  IFVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLN
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Template Sequence  TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLN
Template Known Secondary structure  SS
B


SSSB

B
TT

S

SSSSTTT

GGGTTSGGGSTTS

T
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   85....90.........100.........110.........120.........130.........140.........150.........160....
 
   175....180.........190.........200.........210.........220.........230.........240.........250....
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Query Sequence  PGNQRGIFLVRESETTKGAYSLSIRDWDEIRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTV
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Template Sequence  AENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTV
Template Known Secondary structure  TT

TT

SSSTT
TTT
SSS
SSTTSSS

TTSSS



B
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   165....170.........180.........190.........200.........210.........220.........230.........240....
 
   255....260.........270.........280.........290.........300.........310.........320.........330....
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Query Sequence  CPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVP
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Template Sequence  CPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQ
Template Known Secondary structure 







SS



TTB

GGGTTTTT
TTSS



TTB

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   245....250.........260.........270.........280.........290.........300.........310.........320....
 
   335....340.........350.........360.........370.........380.........390.........400.........410....
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Query Sequence  LYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIAD
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Template Conservation 
 
        

 

   


   
                  
    
  
     

 

   
 
       

 
Template Sequence  LYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVAD
Template Known Secondary structure 
SSS


TTS

TT
S

SGGG
GGG


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   325....330.........340.........350.........360.........370.........380.........390.........400....
 
   415....420.........430.........440.........450.........460.........470.........480.........490....
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Query Sequence  FGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCP
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Template Sequence  FGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCP
Template Known Secondary structure 
TT


SS




TTTT
SGGGS




TTS

SSTT

TT





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   405....410.........420.........430.........440.........450.........460.........470.........480....
 
   495....500.........510.........520.........530.........540...
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Query Sequence  QGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGENL
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Template Conservation        
  

  
   

  


   
   

         
      
Template Sequence  PECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
Template Known Secondary structure  TT

T
SSGGGS

TT
TT



S

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   485....490.........500.........510.........520.........530...
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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