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Job DescriptionQ9HB75
Confidence99.95%DateWed May 9 17:48:56 BST 2012
Rank6Aligned Residues267
% Identity27%Templatec2a0zA_
PDB info PDB header:immune systemChain: A: PDB Molecule:toll-like receptor 3; PDBTitle: the molecular structure of toll-like receptor 3 ligand binding domain
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   12.......20.........30.........40.........50.........60.........70.........80.........90.
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Query Sequence  AAAAAGDASEDSDAGSRALPFLGGNRLSLDLYPGGCQQLLHLCVQQPLQLLQVEFLRLSTHEDPQLLEATLAQLPQSLSC
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Template Conservation   
      
 
    
  

  
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Template Sequence  KCTVSHEVADCSHLKLTQVPDDLPT. . NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ. . . . KLPM
Template Known Secondary structure 

TT

SS

SS

SSS
T..T
S

SS





GGGGTT
TT
S

SS





TT....
TT
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   27..30.........40.........50. ........60.........70.........80.........90...... ...100
 
   92.......100.........110.........120.........130.........140 .........150.........160.. .......
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Query Sequence  LRSLVLKGGQRRDTLGACLRGALTNLPAGLSGLAHLAHLDLSFNSLETL. PACVLQMRGLGALLLSHNCLSE. LPEALGA
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Template Conservation 
  
 

 
 
  
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Template Sequence  LKVLNLQHNELSQLSDKT. . . . . . . . . . . FAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ
Template Known Secondary structure 



SS





TTT...........TTT
TT
S
TTS





S
TTTT
TT



SS







SSS
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   101........110........ .120.........130.........140.........150.........160.........
 
   170.........180.........190.......
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Query Sequence  LPALTFLTVTHNRLQTLPPALGALSTLQ. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Conservation 
  
  
                                                                         
Template Sequence  LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTS
Template Known Secondary structure 
TT



SS



B
GGGTGGGTT
S

S




B
TTTTTTSS

TT



TTTS
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   170.........180.........190.........200.........210.........220.........230.........240.........
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation                                                         
                        
Template Sequence  IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL
Template Known Secondary structure 


TTS



TTTTGGGGGS



TTS



TTTTTT
TT



S

B

TTTTTT
TT


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   250.........260.........270.........280.........290.........300.........310.........320.........
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation                                                                                  
Template Sequence  KRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL
Template Known Secondary structure  TT
B



SSS




TTTTTT
TT



S

B



TTSSTT
TT


TT
BS



SSTTGGGTTS

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   330.........340.........350.........360.........370.........380.........390.........400.........
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation                                                                                  
Template Sequence  HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRR
Template Known Secondary structure 


SS



TTTTTT
TT



SS



SGGGTT
TT



S
S

TTTTTT
TT



S
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   410.........420.........430.........440.........450.........460.........470.........480.........
 
   198.200......... 210.........220....
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . RLDLSQNLLDTL. . . . . . . . . PPEIGGLGSLLELNL
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Template Conservation                    
                       
       
 
  
               
  
  
 
Template Sequence  VALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL
Template Known Secondary structure  S

B
TT
SS
TTTT
TT



SS





TTTTTT
TT



SS

GGGGSTTSTT



TTTT
TT


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   490.........500.........510.........520.........530.........540.........550.........560.........
 
   225....230..... ....240.........250..... ....260.........270.........280 .........290.....
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Query Sequence  ASNRLQSLPAS. LAGLRSLRLLVLHSNLLASV. PADLARLPLLTRLDLRDNQLRDLPP. . . . . ELLDAPFVRLQGNPL
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Template Conservation 
 
 
  
    
  
  
  
 

 
 
       
  
  
  
 

 
 
  
        
  
  
 
  

 
Template Sequence  ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPF
Template Known Secondary structure 
SS





TTTTTT
TT



SS





TTTTTT
TT


TTS





TT
S

S

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   570.........580.........590.........600.........610.........620.........630.........640.......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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