Return to main results Retrieve Phyre Job Id

Job DescriptionQ9HB75
Confidence99.93%DateWed May 9 17:48:56 BST 2012
Rank9Aligned Residues258
% Identity25%Templatec2z64A_
PDB info PDB header:immune systemChain: A: PDB Molecule:toll-like receptor 4; PDBTitle: crystal structure of mouse tlr4 and mouse md-2 complex
Resolution2.84 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   23......30.........40.........50.........60.........70.........80.........90.........100..
Predicted Secondary structure 

















































Query SS confidence 















































































Query Sequence  SDAGSRALPFLGGNRLSLDLYPGGCQQLLHLCVQQPLQLLQVEFLRLSTHEDPQLLEATLAQLPQSLSCLRSLVLKGGQR
Query Conservation     

  

 
  
   
         
  
       
  
  
 

 
    
    
  

  
  
  
 
  
  
Alig confidence 













..












































....














Template Conservation 
   
  

  
  .. 
  
 

 
 
  
    
  
  
  
 

 
 
  
    
 .... 
  
  
 

 
 
Template Sequence  MDQKLSKVPDDIPS. . STKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWH. . . . GLHHLSNLILTGNPI
Template Known Secondary structure  SSS

SS

SSS
S..S



SS



TTTTSS
TT


SS




TTTTT....T
TT


TT


Template Predicted Secondary structure 













..





























....











Template SS confidence 















































































   40.........50... ......60.........70.........80.........90........ .100.........110...
 
   103......110.........120.........130.........140.. .......150.........160.. .......170.........
Predicted Secondary structure 































.













..










Query SS confidence 







































.



















. .
















Query Sequence  RDTLGACLRGALTNLPAGLSGLAHLAHLDLSFNSLETLPA. CVLQMRGLGALLLSHNCLSE. . LPEALGALPALTFLTVT
Query Conservation           
 
  

     
  
  



 
 
  

 . 
  
  
  
 
  
 
  ..

  
  
  
  
 

Alig confidence 






...........





















.



















..
















Template Conservation    
    ...........
  
  
  
 
  
 
  
       
  
  
 
  
                
  
   
Template Sequence  QSFSPGS. . . . . . . . . . . FSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAHNFIHSCKLPAYFSNLTNLVHVDLS
Template Known Secondary structure 



TTT...........TTT
TT


TTS



TTT


TT
TT



SS







GGGGT
TT


T
Template Predicted Secondary structure 



...........
















































Template SS confidence 















































































   114.....120 .........130.........140.........150.........160.........170.........180..
 
   180.........190.......
Predicted Secondary structure 













..............................................................
Query SS confidence 

















. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  HNRLQTLPPALGALSTLQ. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation   
 
  

     
  
 ..............................................................
Alig confidence 

















..............................................................
Template Conservation   
                                                                              
Template Sequence  YNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQDQAFQGIKLHELTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEF
Template Known Secondary structure  TS



TTTTTTTTT
TT



TT




TTTTTTS

SST
S

Template Predicted Secondary structure 








































































Template SS confidence 















































































   183......190.........200.........210.........220.........230.........240.........250.........260..
 
  
Predicted Secondary structure  ................................................................................
Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation                                               
                                  
Template Sequence  KDERNLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLANVSAMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQ
Template Known Secondary structure  TTSS

S


GGGGTTTTTS


SS

TTGGG
GGGTT
SS









TT


SS


SS
Template Predicted Secondary structure 















































































Template SS confidence 















































































   263......270.........280.........290.........300.........310.........320.........330.........340..
 
  
Predicted Secondary structure  ................................................................................
Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation                                   
                                             
Template Sequence  FPTLDLPFLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFSGCCSYSDLGTNSLRHLDLSFNGAIIMSANFMGLEEL
Template Known Secondary structure 





TT

SBSS

B





TT



SBS
B
SS
S




S
S
S

TT
TT
Template Predicted Secondary structure 











































































Template SS confidence 















































































   343......350.........360.........370.........380.........390.........400.........410.........420..
 
   198.200...... ...210.........220.....
Predicted Secondary structure  ..................................................





..











Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .








. .


















Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . RLDLSQNLL. . DTLPPEIGGLGSLLELNLA
Query Conservation  .................................................. 
 

 
 
..  

  
  
  
  
 

Alig confidence  ..................................................








..


















Template Conservation                          
                       
  
 
  
                
  
 

Template Sequence  QHLDFQHSTLKRVTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKDNTLSNVFANTTNLTFLDLS
Template Known Secondary structure 

TTSSTTTS
TTTT
TT


TTS



S
TTTT
TT


TT
GGG
STTSS
TT
S
T
Template Predicted Secondary structure 












































































Template SS confidence 















































































   423......430.........440.........450.........460.........470.........480.........490.........500..
 
   226...230..... ....240.........250..... ....260.........270.........280 .........290.......
Predicted Secondary structure 







.














.













....










Query SS confidence 









.



















.
























. . . .
















Query Sequence  SNRLQSLPAS. LAGLRSLRLLVLHSNLLASV. PADLARLPLLTRLDLRDNQLRDLPP. . . . ELLDAPFVRLQGNPLGE
Query Conservation   
 
  

  .
  
  
  
 

 
 
  
.
  
  
  
  



 
 
  

 ....    
  
 
 



  
Alig confidence 









.



















.
























....
















Template Conservation   
 
  
    
  
  
  
 

 
 
  
    
  
  
  
 

 
 
             
  
 
  
   
Template Sequence  KCQLEQISWGVFDTLHRLQLLNMSHNNLLFLDSSHYNQLYSLSTLDCSFNRIETSKGILQHFPKSLAFFNLTNNSVAC
Template Known Secondary structure  T




TTTTTT
TT



SS


GGGTTT
TT



SS


S
GGGS
TT



S

B

Template Predicted Secondary structure 























































Template SS confidence 













































































   503......510.........520.........530.........540.........550.........560.........570.........580
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions