|   |   |
1510 | . | . | . | . | . | . | . | . | . | 1520 | . | . | . | . | . | . | . | . | . | 1530 | . | . | . | . | . | . | . | . | . | 1540 | . | . | . | . | |
. | . | . | . | . | 1550 | . | . | . | . | . | . | . | . | . | 1560 | . | . | . | . | . | . | . | . | . | 1570 | . | . | . | . | |
|
. | . | . | . | . | 1580 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
| . |
|  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
P | Q | P | C | L | V | R | V | Y | M | V | R | A | I | N | L | Q | P | Q | D | Y | N | G | L | C | D | P | Y | V | I | L | K | L | G | K | . |
T | E | L | G | N | R | D | M | Y | Q | P | N | T | L | D | P | I | F | G | M | M | F | E | L | T | C | N | I | P | L | . |
. |
E | K | D | L | E | I | Q | L | Y | D | F | D |
| Query Conservation |   |
|   |   |   |
|
|
|
|
|
|
|   |
|   |
|
|   |
|   |
|   |
|
|   |
|
|
|
|
|   |
|   |
|
|   | . |
|   |
|   |
|
|   |   |
|
|   |
|
|
|
|
|   |
|   |   |   |
|
|
|   |   |   |
|
|   | . | . |
|
|   |
|   |
|   |
|
|
|   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |
|   |
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |
|   |   |
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |
|
|   |
|   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |
| Template Sequence |   |
Y | G | S | D | Q | L | V | V | R | I | L | Q | A | L | D | L | P | A | K | D | S | N | G | F | S | D | P | Y | V | K | I | Y | L | L | P | D | R | K | K | K | F | Q | T | K | V | H | R | K | T | L | N | P | I | F | N | E | T | F | Q | F | S | V | P | L | A | E | L | A | Q | R | K | L | H | F | S | V | Y | D | F | D |
| Template Known Secondary structure |   |
S | S | S |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| S | T | T | S |
|
|
|  |  |  |  |  |  |
| T | T | S | T | T | S |
|  |  |
|
|
|
|
| S |
| S | S |
|  |  |  |  |  |  |  |  |  |
|
| G | G | G | G | S | S |
|
|
|  |  |  |  |  |  |
|
|
| Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
309 | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . |
|   |
|   |   |
1587 | . | . | 1590 | . | . | . | . | . | . | . | . | . | 1600 | . | . | . | . | . | . | . | . | . | 1610 | . | . | . | . | . | . | . | . | . | 1620 | . | . | . | . | . | . | . | . | . | 1630 | . | . | . | . | . | . | . | . | . | 1640 | . | . | . | . | . | . | . | . | . | 1650 | . | . | . | . | . | . | . | . | . | 1660 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | F | S | P | D | D | K | I | G | T | T | V | I | D | L | E | N | R | L | L | S | G | F | G | A | H | C | G | L | S | K | S | Y | C | Q | S | G | P | F | R | W | R | D | Q | M | P | P | S | Y | L | L | E | R | Y | A | K | R | K | G | L | P | P | P | L | F | S | P | E | E | D | A | V | F | Y | N | G | K | K | F | K |
| Query Conservation |   |
  |   |   |   |
|
|
|
|
|   |
|   |
|
|
|
|
|
|   |   |
|
|   |
|
|   |
|
|
|   |   |   |
|   |   |   |
|   |
|   |
|
|
|   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
  |   |   |   |
|   |   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Sequence |   |
R | F | S | R | H | D | L | I | G | Q | V | V | L | D | N | L | L | E | L | A | E | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Template Known Secondary structure |   |
S | S | S |
|
|
|  |  |  |  |  |  |
|
|
| T | T | G | G | G | S | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
389 | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |
1667 | . | . | 1670 | . | . | . | . | . | . | . | . | . | 1680 | . | . | . | . | . | . | . | . | . | 1690 | . | . | . | . | . | . | . | . | . | 1700 | . | . | . | . | . | . | . | . | . | 1710 | . | . | . | . | . | . | . | . | . | 1720 | . | . | . | . | . | . | . | . | . | 1730 | . | . | . | . | . | . | . | . | . | 1740 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | Q | S | F | E | P | K | T | P | T | V | H | G | L | G | P | K | K | E | R | L | A | L | Y | L | L | H | T | Q | G | L | V | P | E | H | V | E | T | R | T | L | Y | S | H | S | Q | P | G | I | D | Q | G | K | V | Q | M | W | V | D | I | F | P | K | K | L | G | P | P | G | P | Q | V | N | I | N | P | R | K | P | K |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |
|   |
| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | P | D | R | P | L | W | R | D | I | L | E | G | G | S | E | K | A | D | L | G | E | L | N | F | S | L | C | Y | L | P | T | A | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| S | S |
|
|
|
|  |  |
| B |
|
| S | S |
|
| S |
|
|
|  |  |  |  |  |  |  |  |  | T | T | T | T | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
411 | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |
1747 | . | . | 1750 | . | . | . | . | . | . | . | . | . | 1760 | . | . | . | . | . | . | . | . | . | 1770 | . | . | . | . | . | . | . | . | . | 1780 | . | . | . | . | . | . | . | . | . | 1790 | |
|
. | . | . | . | . | . | . | . | . | 1800 | . | . | . | . | . | . | . | . | . | 1810 | . | . | . | . | . | . | . | . | . | 1820 | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | K | A | S | E | H | S | G | H | R | Y | E | L | R | C | I | I | W | K | T | A | N | V | D | L | V | D | D | N | L | S | R | E | K | T | S | D | I | Y | I | K | G | W | L | . |
. |
Y | G | L | E | K | D | M | Q | K | T | D | I | H | Y | H | S | L | T | G | E | A | D | F | N | W | R | F | I | F | T | M | D | Y | L |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |
|   |   |
|   |
|   |
|   |   |   |   |
|   |   |   |
|
|
|
|
|
|
|
|
| . | . |   |
|   |   |   |   |   |
|   |
|
|
|
|
|   |
|   |   |
|   |
|   |
|
|
|
|   |
|
|   |   |   |   |   |
| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |   |
| . | . |
|   |   |
|   |   |   |   |
|   |
|   |   |   |
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | L | T | V | T | I | I | K | A | S | N | L | K | A | M | D | L | T | . |
. |
. |
. |
G | F | S | D | P | Y | V | K | A | S | L | I | S | E | G | R | R | L | K | K | R | K | T | S | I | K | K | N | T | L | N | . |
. |
P | T | Y | N | E | A | L | V | F | D | V | A | P | E |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
| S | S | S | . | . | . | . | S |
|
|
|  |  |  |  |  |
|
|
| T | T |
|
| T | T | S |
|  |  |
|
|
|
|
| S |
| S | S | . | . |
|  |  |  |  |
|
|
|
|
|
|
| S | G |
| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|
|
|
|
|
|
445 | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | |
|
|
|
. | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | |
|
. | . | . | . | . | . | 500 | . | . | . | . | . | . | . |
|   |
|   |   |
1825 | . | . | . | . | 1830 | . | . | . | . | . | . | . | . | . | 1840 | . | . | . | . | . | . | . | . | . | 1850 | . | . | . | . | . | . | . | . | . | 1860 | . | . | . | . | . | . | . | . | . | 1870 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | A | E | R | T | C | V | Q | S | Q | K | D | Y | I | W | S | L | D | A | T | S | M | K | F | P | A | R | L | I | I | Q | V | W | D | N | D | I | F | S | P | D | D | F | L | G | V | L | E | L | D | L | S | D |
| Query Conservation |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|   |
|   |   |
|   |
|
|   |
|
|   |   |   |
|
|
|   |   |
| Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|   |
|   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |
|   |   |
| Template Sequence |   |
S | V | E | N | V | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | S | I | A | V | V | D | Y | D | C | I | G | H | N | E | V | I | G | V | C | R | V | G | P | E | A |
| Template Known Secondary structure |   |
G | G | G | S |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |
|
| S | S | S |
|
|  |  |  |  |  |
|
|
| S | S |
| T |
| Template Predicted Secondary structure |   |
 |  |
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
508 | . | 510 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . |
|   |