|   |   |
268 | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | |
|
|
|
. | . | 340 | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
| Query Sequence |   |
P | S | E | L | A | F | I | K | E | I | G | S | G | Q | F | G | V | V | H | L | G | E | W | R | S | H | I | Q | V | A | I | K | A | I | N | E | G | S | M | S | E | E | D | F | I | E | E | A | K | V | M | M | K | L | S | H | S | K | L | V | Q | L | Y | G | V | C | I | Q | R | K | . |
. |
. |
. |
P | L | Y | I | V | T |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   | . | . | . | . |   |   |   |
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   | . |   |
|   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
| Template Sequence |   |
A | R | T | I | V | L | Q | E | S | I | G | K | G | R | F | G | E | V | W | R | G | K | W | . |
R | G | E | E | V | A | V | K | I | F | S | S | R | E | E | R | S | W | F | R | E | A | E | I | Y | Q | T | V | M | L | R | H | E | N | I | L | G | F | I | A | A | D | N | K | D | N | G | T | W | T | Q | L | W | L | V | S |
| Template Known Secondary structure |   |
 | T | T |
|  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | . | T | T |  |  |  |  |  |  |  |  |
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| T | T | B |
|
|  |  |  |  |  |  |
|
|
| G | G | G |
|
|  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . |
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
202 | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | |
. | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 |
|   |
|   |   |
344 | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | F | M | E | N | G | C | L | L | N | Y | L | R | E | N | K | G | K | L | R | K | E | M | L | L | S | V | C | Q | D | I | C | E | G | M | E | Y | L | E | R | N | . |
. |
. |
. |
. |
. |
. |
. |
G | Y | I | H | R | D | L | A | A | R | N | C | L | V | S | S | T | C | I | V | K | I | S | D | F | G | M | T | R | Y | V |
| Query Conservation |   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|
|   |   | . | . | . | . | . | . | . | . |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |   |   |
| Template Sequence |   |
D | Y | H | E | H | G | S | L | F | D | Y | L | N | R | Y | . |
. |
T | V | T | V | E | G | M | I | K | L | A | L | S | T | A | S | G | L | A | H | L | H | M | E | I | V | G | T | Q | G | K | P | A | I | A | H | R | D | L | K | S | K | N | I | L | V | K | K | N | G | T | C | C | I | A | D | L | G | L | A | V | R | H |
| Template Known Secondary structure |   |
|
|
| T | T |
| B |  |  |  |  |  |  |  |
| . | . |
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| S | S | S |
|
|
|  |  |  |
| S |
|
|
| G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
|
| T | T |
|  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
281 | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | |
|
. | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . |
|   |
|   |   |
416 | . | . | . | 420 | . | . | . | . | . | . | . | . | |
|
|
. | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|
| . | . | . |
|  |  |  |
|
|  |  |  |  |  |
|
|
| . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Query Sequence |   |
L | D | D | E | Y | V | S | S | F | G | A | K | F | . |
. |
. |
P | I | K | W | S | P | P | E | V | F | L | F | N | K | . |
. |
. |
. |
. |
. |
Y | S | S | K | S | D | V | W | S | F | G | V | L | M | W | E | V | F | T | E | G | K | M | P | F | E | N | K | S | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |
|   |
|
|
|   |
|   |   |   |   | . | . | . | . | . | . |   |
|   |
|
|
|
|
|
|   |
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|   |
|
|   |
| . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
D | S | A | T | D | T | I | D | I | A | P | N | H | R | V | G | T | K | R | Y | M | A | P | E | V | L | D | D | S | I | N | M | K | H | F | E | S | F | K | R | A | D | I | Y | A | M | G | L | V | F | W | E | I | A | R | . |
R | C | S | I | G | G | I | H | E | D | Y | Q | L | P | Y | Y | D | L | V | P | S | D | P | S |
| Template Known Secondary structure |   |
 | G | G | G | T |  |  |  |
| T | T |
| S |
|
| S |
| G | G | G |
|
|  |  |  |  |  | T |
|
|
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | T | B |
| B | T | T | B |
|
|
|
|
|
| T | T | T | T | T | S |
| S | S |
|
|
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
359 | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | |
. | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . |
|   |
|   |   |
|
|
473 | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
. | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
L | Q | V | V | E | A | I | S | E | G | F | R | L | Y | R | P | H | L | . |
. |
. |
. |
. |
A | P | M | S | I | Y | E | V | M | Y | S | C | W | H | E | K | P | E | G | R | P | T | F | A | E | L | L | R | A | V | T | E | I | A | E | T |
| Query Conservation |   |
. | . |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   | . | . | . | . | . |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |
|   |
|   |
| Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|
|   |
|
|   |   |   |
|   |   |
|   |   |   |
| Template Sequence |   |
V | E | E | M | R | K | V | V | C | E | Q | K | L | R | P | N | I | P | N | R | W | Q | S | C | E | A | L | R | V | M | A | K | I | M | R | E | C | W | Y | A | N | G | A | A | R | L | T | A | L | R | I | K | K | T | L | S | Q | L | S | Q | Q |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T | S |
|
|
|
|
|
|
| S | G | G | G | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
438 | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . |
|   |