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Job DescriptionP42681
Confidence100.00%DateThu Apr 26 09:52:37 BST 2012
Rank40Aligned Residues260
% Identity58%Templatec3sxrA_
PDB info PDB header:transferase/transferase inhibitorChain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx; PDBTitle: crystal structure of bmx non-receptor tyrosine kinase complex with2 dasatinib
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   262.......270.........280.........290.........300.........310.........320.........330.........340.
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Query Sequence  EKWEIDPSELAFIKEIGSGQFGVVHLGEWRSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYI
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Template Sequence  GHMELKREEITLLKELGSVVKLGKW. . . . KGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYI
Template Known Secondary structure 


B

GGG

....TTT
BTTB
S

TTB


SSSS
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   408.410.........420.........430.. .......440.........450.........460.........470.........480...
 
   342.......350.........360.........370.........380.........390.........400.........410.........420.
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Query Sequence  VTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDEYV
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Template Sequence  VTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYV
Template Known Secondary structure 

TT
BGGGS
TTTT
SGGG
TTS


TTT

TT
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   488.490.........500.........510.........520.........530.........540.........550.........560.......
 
   422.......430.........440.........450.........460.........470.........480.........490.........500.
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Query Sequence  SSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYS
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Template Sequence  SSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKMPYDLYTNSEVVLKVSQGHRLYRPHLASDTIYQIMYS
Template Known Secondary structure 

S



GGG

STTTTS

TTTT

T





TTS
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   568.570.........580.........590.........600.........610.........620.........630.........640.......
 
   502.......510.........520.....
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Query Sequence  CWHEKPEGRPTFAELLRAVTEIAE
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Template Sequence  CWHELPEKRPTFQQLLSSIEPLRE
Template Known Secondary structure  TT
SSGGGS

GGGT
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   648.650.........660.........670.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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