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Job DescriptionP42681
Confidence100.00%DateThu Apr 26 09:52:37 BST 2012
Rank180Aligned Residues231
% Identity24%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   264.....270.........280.........290.. .......300.........310.........320.........330.........340..
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Query Sequence  WEIDPSELAFIKEIGSGQFGVVHLGEWRS. HIQVAIKAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIV
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Template Sequence  KQVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILK. . . . . . KEVIVANRVLQNSRHPFLTALKYSFQTHDRLCFV
Template Known Secondary structure  T


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   112.......120.........130.........140.........150. ........160.........170.........180.....
 
   343......350.........360.........370.........380.... .....390.........400.........410.........420.
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Query Sequence  TEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERN. GYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDEYV
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Template Sequence  MEYANGGELFFHLSRER. VFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEPE. . . . .
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   227..230.........240... ......250.........260.........270.........280.........290.........300
 
   422.......430.........440.........450.........460.........470.........480.........490.........500.
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Query Sequence  SSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYS
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Template Sequence  . . . . . . . . . . YLAPEVLEDNDYGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLFELILMEE. IRFPRTLGPEAKSLLSG
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   315....320.........330.........340.... .....350.........360..... ....370.........380..
 
   502.......510 ........
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Query Sequence  CWHEKPEGR. . . . . PTFAELLR
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Template Sequence  LLKKDPKQRLGGGSEDAKEIMQ
Template Known Secondary structure  T
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   383......390.........400....
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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