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Job DescriptionP42681
Confidence100.00%DateThu Apr 26 09:52:37 BST 2012
Rank164Aligned Residues251
% Identity22%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  SELAFIKEIGSGQFGVVHLGEWRSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGV. . . . CIQRKPLYIVTE
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Template Sequence  RDITLLECVGKGRYGEVWRGSW. QGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITH
Template Known Secondary structure  TTTT.TT
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Query Sequence  FMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGY. . . . . . . . IHRDLAARNCLVSSTCIVKISDFGMTRYVL
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Template Sequence  YHEMGSLYDYLQLT. . TLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHS
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   285....290........ .300.........310.........320.........330.........340.........350.........360..
 
   417..420.........430.........440.. .......450.........460.........470..
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Query Sequence  . . . DDEYVSSFGAKFPIKWSPPEVFLFNK. . . . . . YSSKSDVWSFGVLMWEVFTEGKMPFENKSN. . . . . . . . . . . . . . .
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Template Sequence  QSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPNDPSF
Template Known Secondary structure  TTTT








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   363......370.........380.........390.........400.........410...... ...420.........430.........440.
 
   473......480.........490 .........500.........510.........520...
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Query Sequence  LQVVEAISEGFRLYRPHL. . . . . . APMSIYEVMYSCWHEKPEGRPTFAELLRAVTEI
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Template Sequence  EDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
Template Known Secondary structure  TTS






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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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