Job Description P42681 Confidence 100.00% Date Thu Apr 26 09:52:37 BST 2012 Rank 37 Aligned Residues 257 % Identity 35% Template c3lxkA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 Resolution 2.00 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		266	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290						.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.		.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.			.	.
Predicted Secondary structure																											.	.	.	.	.																			.																												.	.
Query SS confidence																											.	.	.	.	.																			.																												.	.
Query Sequence		I	D	P	S	E	L	A	F	I	K	E	I	G	S	G	Q	F	G	V	V	H	L	G	E	W	.	.	.	.	.	R	S	H	I	Q	V	A	I	K	A	I	N	E	G	S	M	S	E	.	E	D	F	I	E	E	A	K	V	M	M	K	L	S	H	S	K	L	V	Q	L	Y	G	V	C	I	Q	.	.	R	K
Query Conservation																											.	.	.	.	.																			.																												.	.
Alig confidence																											.	.	.	.	.																			.																												.	.
Template Conservation
Template Sequence		F	E	E	R	H	L	K	Y	I	S	Q	L	G	K	G	N	F	G	S	V	E	L	C	R	Y	D	P	L	G	D	N	T	G	A	L	V	A	V	K	Q	L	Q	H	S	G	P	D	Q	Q	R	D	F	Q	R	E	I	Q	I	L	K	A	L	H	S	D	F	I	V	K	Y	R	G	V	S	Y	G	P	G	R	Q
Template Known Secondary structure				G	G	G											T	T										T	T	S	S	S		S									S	S																		T				T	T	B									S	S	S	S
Template Predicted Secondary structure
Template SS confidence
		817	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.
		338	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.
Predicted Secondary structure																																																																																	.
Query SS confidence																																																																																	.
Query Sequence		P	L	Y	I	V	T	E	F	M	E	N	G	C	L	L	N	Y	L	R	E	N	K	G	K	L	R	K	E	M	L	L	S	V	C	Q	D	I	C	E	G	M	E	Y	L	E	R	N	G	Y	I	H	R	D	L	A	A	R	N	C	L	V	S	S	T	C	I	V	K	I	S	D	F	G	M	T	R	Y	V	L	.
Query Conservation																																																																																	.
Alig confidence																																																																																	.
Template Conservation
Template Sequence		S	L	R	L	V	M	E	Y	L	P	S	G	C	L	R	D	F	L	Q	R	H	R	A	R	L	D	A	S	R	L	L	L	Y	S	S	Q	I	C	K	G	M	E	Y	L	G	S	R	R	C	V	H	R	D	L	A	A	R	N	I	L	V	E	S	E	A	H	V	K	I	A	D	F	G	L	A	K	L	L	P	L
Template Known Secondary structure											T	T		B									G	G	G																							T	T				S			S	G	G	G						T	T								T	T						T
Template Predicted Secondary structure
Template SS confidence
		897	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.
			417	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.											470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.
Predicted Secondary structure		.																																																						.	.	.	.	.	.	.	.	.	.
Query SS confidence		.																																																						.	.	.	.	.	.	.	.	.	.
Query Sequence		.	D	D	E	Y	V	S	S	F	G	A	K	F	P	I	K	W	S	P	P	E	V	F	L	F	N	K	Y	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	V	F	T	E	G	K	M	P	F	E	N	.	.	.	.	.	.	.	.	.	.	K	S	N	L	Q	V	V	E	A	I	S	E	G	F	R	L
Query Conservation		.																																																						.	.	.	.	.	.	.	.	.	.
Alig confidence		.																																														.								.	.	.	.	.	.	.	.	.	.
Template Conservation																																																.
Template Sequence		D	K	D	Y	Y	V	V	R	E	P	G	Q	S	P	I	F	W	Y	A	P	E	S	L	S	D	N	I	F	S	R	Q	S	D	V	W	S	F	G	V	V	L	Y	E	L	F	T	.	Y	C	D	K	S	C	S	P	S	A	E	F	L	R	M	M	V	P	A	L	S	R	L	L	E	L	L	E	E	G	Q	R	L
Template Known Secondary structure		T		S					S	S				S		G	G	G																													T	.	T	T		G	G	G	S																						T	T
Template Predicted Secondary structure																																																.
Template SS confidence
		977	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.		.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.
		486	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	R	P	H	L	A	P	M	S	I	Y	E	V	M	Y	S	C	W	H	E	K	P	E	G	R	P	T	F	A	E	L	L	R	A	V	T	E	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	A	P	P	A	C	P	A	E	V	H	E	L	M	K	L	C	W	A	P	S	P	Q	D	R	P	S	F	S	A	L	G	P	Q	L	D	M	L
Template Known Secondary structure					T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1061	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions