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Job DescriptionP42681
Confidence100.00%DateThu Apr 26 09:52:37 BST 2012
Rank152Aligned Residues256
% Identity36%Templatec3kexA_
PDB info PDB header:transferaseChain: A: PDB Molecule:receptor tyrosine-protein kinase erbb-3; PDBTitle: crystal structure of the catalytically inactive kinase2 domain of the human epidermal growth factor receptor 33 (her3)
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   265....270.........280.........290..... ....300...... ...310.........320.........330.......
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Query Sequence  EIDPSELAFIKEIGSGQFGVVHLGEWRSHIQ. . . . . VAIKAINEGSM. . SEEDFIEEAKVMMKLSHSKLVQLYGVCIQRK
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Template Sequence  IFKETELRKLKVLGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCPGSS
Template Known Secondary structure  B

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   684.....690.........700.........710.........720.........730.........740.........750.........760...
 
   338.340.........350.........360.........370.........380.........390.........400.........410.......
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Query Sequence  PLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLD
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Template Sequence  L. QLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPP
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TT
BSSSGGGS
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   764 .....770.........780.........790.........800.........810.........820.........830.........840..
 
   418.420.........430.........440.........450.........460.........470.........480.........490.......
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Query Sequence  DEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYE
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Template Sequence  DDKQLLTPIK. . . . WMALESIHFGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYM
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   843......850.. .......860.........870.........880.........890.........900.........910........
 
   498.500.........510.........520.....
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Query Sequence  VMYSCWHEKPEGRPTFAELLRAVTEIAE
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Template Sequence  VMVKCWMIDENIRPTFKELANEFTRMAR
Template Known Secondary structure  T
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   924.....930.........940.........950.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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