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Job DescriptionP42681
Confidence100.00%DateThu Apr 26 09:52:37 BST 2012
Rank194Aligned Residues248
% Identity36%Templatec3c1xA_
PDB info PDB header:transferaseChain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor
Resolution2.17 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   262.......270 .........280.........290.... .....300........ .310.........320.........330...
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Query Sequence  EKWEIDPSE. . LAFIKEIGSGQFGVVHLGEWRSHI. . . . QVAIKAINEGSMSE. . EDFIEEAKVMMKLSHSKLVQLYGVC
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Template Sequence  QHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC
Template Known Secondary structure  TTTB

STT

SSSTTT

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   1067..1070.........1080.........1090.........1100.........1110.........1120.........1130.........1140......
 
   334..... 340.........350.........360.........370.........380.........390.........400.........410..
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Query Sequence  IQRKPL. YIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMT
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Template Sequence  LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKFLASKKFVHRDLAARNCMLDEKFTVKVADFLPV
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   1147..1150.........1160.........1170.........1180.........1190.........1200.........1210.........1220......
 
   413......420.........430.........440.........450.........460.........470.........480.........490..
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Query Sequence  RYVLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAP
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Template Sequence  . . . . . . . . . . . . . . . . . . KWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCP
Template Known Secondary structure  ..................GGS




TTS

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   1248.1250.........1260.........1270.........1280.........1290.........1300.........
 
   493......500.........510.........520.......
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Query Sequence  MSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAETW
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Template Sequence  DPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTF
Template Known Secondary structure  T
SSGGGS

T
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   1310.........1320.........1330.........1340....
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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