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Job DescriptionP42681
Confidence100.00%DateThu Apr 26 09:52:37 BST 2012
Rank157Aligned Residues258
% Identity37%Templatec2yhvA_
PDB info PDB header:transferaseChain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of l1196m mutant anaplastic lymphoma kinase
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   262.......270.........280.........290.........300........ .310.........320.........330.........
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Query Sequence  EKWEIDPSELAFIKEIGSGQFGVVHLGEWRSHIQVAIKAINEGSMSE. . EDFIEEAKVMMKLSHSKLVQLYGVCIQRKPL
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Template Sequence  DLKEVPRKNITL. . . IRGLAFGEVYEGQV. . PLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPR
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   1107..1110........ .1120.........1130.. .......1140.........1150.........1160.........1170.........1180.
 
   340.........350....... ..360.........370.........380.........390.........400.........410...
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Query Sequence  YIVTEFMENGCLLNYLRE. . . . . . NKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTR
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Template Sequence  FILMELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDF.
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   1193......1200.........1210.........1220.........1230.........1240.........1250.........1260.........1270.
 
   414.....420.........430.........440.........450.........460.........470.........480.........490...
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Query Sequence  YVLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPM
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Template Sequence  . GMARDIYRGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPG
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   1272.......1280.........1290.........1300.........1310.........1320.........1330.........1340.........1350
 
   494.....500.........510.........520......
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Query Sequence  SIYEVMYSCWHEKPEGRPTFAELLRAVTEIAET
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Template Sequence  PVYRIMTQCWQHQPEDRPNFAIILERIEYCTQD
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   1357..1360.........1370.........1380.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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