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Job DescriptionP42681
Confidence100.00%DateThu Apr 26 09:52:37 BST 2012
Rank195Aligned Residues257
% Identity38%Templatec2xbaA_
PDB info PDB header:transferaseChain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of human anaplastic lymphoma kinase in complex2 with pha-e429
Resolution1.95 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   264.....270.........280.. .......290.........300........ .310.........320.........330.......
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Query Sequence  WEIDPSELAFIKEIGSGQF. . . . GVVHLGEWRSHIQVAIKAINEGSMSE. . EDFIEEAKVMMKLSHSKLVQLYGVCIQRK
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Template Sequence  FAGKTSSISDLKEVPRKNITLIRGLVYEGQVSP. LQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSL
Template Known Secondary structure  TT
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   1098.1100.........1110.........1120.........1130 .........1140.........1150.........1160.........1170......
 
   338.340.........350...... ...360.........370.........380.........390.........400.........410.
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Query Sequence  PLYIVTEFMENGCLLNYLR. . . . . . ENKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGM
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Template Sequence  PRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGD
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   1191........1200.........1210.........1220.........1230.........1240.........1250.........1260.........1270
 
   412.......420.........430.........440.........450.........460.........470.........480.........490.
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Query Sequence  TRYVLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLA
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Template Sequence  F. . . . . . GMARDIYAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNC
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   1271 ........1280.........1290.........1300.........1310.........1320.........1330.........1340....
 
   492.......500.........510.........520.......
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Query Sequence  PMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAETW
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Template Sequence  PGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDP
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   1355....1360.........1370.........1380.........1390
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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