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Job DescriptionP42681
Confidence100.00%DateThu Apr 26 09:52:37 BST 2012
Rank112Aligned Residues238
% Identity24%Templatec2r7bA_
PDB info PDB header:signaling protein, transferaseChain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   268.270.........280.........290 .........300.. .......310.........320.........330.........340..
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Query Sequence  PSELAFIKEIGSGQFGVVHLGEW. RSHIQVAIKAIN. . . . EGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIV
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Template Sequence  PEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFG
Template Known Secondary structure  GGG
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   7980.........90.........100.........110.........120.........130.........140.........150........
 
   343......350.........360.........370.........380.........390.........400.........410.........420..
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Query Sequence  TEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDEYVS
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Template Sequence  LSYAKNGELLKYIRKIG. SFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL. . . . . . .
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   159160.........170..... ....180.........190.........200.........210.........220.........230
 
   423......430.........440.........450.........460.........470.........480.........490.........500..
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Query Sequence  SFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSC
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Template Sequence  . . . FVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVA. GLPPFRAGNEYLIFQKIIKLE. YDFPEKFFPKARDLVEKL
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   242.......250.........260.........270....... ..280.........290........ .300.........310......
 
   503......510........
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Query Sequence  WHEKPEGRPTFAELLR
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Template Sequence  LVLDATKRLGCEEMEG
Template Known Secondary structure  S
SSTTSSTTSGGGTT
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   317..320.........330..
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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