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Job DescriptionP42681
Confidence100.00%DateThu Apr 26 09:52:37 BST 2012
Rank245Aligned Residues250
% Identity22%Templatec2ojiA_
PDB info PDB header:transferaseChain: A: PDB Molecule:mitogen-activated protein kinase 1; PDBTitle: crystal structure of erk2 in complex with n-benzyl-4-(4-(3-2 chlorophenyl)-1h-pyrazol-3-yl)-1h-pyrrole-2-carboxamide
Resolution2.60 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   264.....270.........280.........290..... ....300........ .310.........320.........330.......
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Query Sequence  WEIDPSELAFIKEIGSGQFGVVHLGEWRSHIQ. VAIKAINEGSMSE. . EDFIEEAKVMMKLSHSKLVQLYGVCIQRK. . .
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Template Sequence  FDVG. PRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQ
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   17..20 .........30.........40.........50.........60.........70.........80.........90.....
 
   338.340.........350.........360.........370.........380.........390.........400.........410.....
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Query Sequence  . . PLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYV
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Template Sequence  MKDVYIVQDLMETDLYKLLKT. . . QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVA
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   96...100.........110...... ...120.........130.........140.........150.........160.........170..
 
   416...420........ .430.........440.........450.........460.........470.........480........
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Query Sequence  LDDEYVSSFGAKF. . . PIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRP. . . .
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Template Sequence  DPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS. NRPIFPGKHYLDQLNHILGILGSPSQEDLN
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GGG
B

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   173......180.........190.........200.........210.........220. ........230.........240.........250.
 
   489490.........500.........510........
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . HLAPMSIYEVMYSCWHEKPEGRPTFAELLR
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Template Sequence  CIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALA
Template Known Secondary structure  S


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   252.......260.........270.........280.........290.........300.......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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