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Job DescriptionP42681
Confidence100.00%DateThu Apr 26 09:52:37 BST 2012
Rank16Aligned Residues265
% Identity35%Templatec2ivsA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   262.......270.........280.........290. ........300........ .310.........320.........330...
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Query Sequence  EKWEIDPSELAFIKEIGSGQFGVVHLGEWR. . . . . . SHIQVAIKAINEGSMSE. . EDFIEEAKVMMKLSHSKLVQLYGVC
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Template Sequence  PKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGAC
Template Known Secondary structure  TTTB

GGG
SSSTGGG
SS

TT

TT


TTB

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   715....720.........730.........740.........750.........760.........770.........780.........790....
 
   334.....340.........350......... 360.........370.........380.........390.........400......
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Query Sequence  IQRKPLYIVTEFMENGCLLNYLRENK. . . . . . . GKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKI
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Template Sequence  SQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLRALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKI
Template Known Secondary structure 
SSSS


TT
BTTTSTT


TT



SGGGTTT
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   795....800.........810.........820.........830.........840.........850.........860.........870....
 
   407..410.... .....420.........430.........440.........450.........460.........470.........480.....
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Query Sequence  SDFGMTRY. VLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRL
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Template Sequence  SDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRM
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TT

TTTS

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S
GGG



TTS

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   891........900.........910.........920.........930.........940.........950.........960.........970
 
   486...490.........500.........510.........520......
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Query Sequence  YRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAET
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Template Sequence  ERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVK
Template Known Secondary structure 


TT

T
SSGGGS

T
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   971........980.........990.........1000.........1010.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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