Job Description P42681 Confidence 100.00% Date Thu Apr 26 09:52:37 BST 2012 Rank 1 Aligned Residues 444 % Identity 39% Template c2fo0A_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase Resolution 2.27 Å

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		74	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	L	P	P	S	E	V	A	E	E	K	I	Q	V	K	A	L	Y	D	F	L	P	R	E	P	C	N	L	A	L	R	R	A	E	E	Y	L	I	L	E	K	Y	N	P	H	W	W	K	A	R	D	R	L	G	N	E	G	L	I	P	S	N	Y	V	T	E	N	K	I	T	N	L	E	I	Y	E	W	Y	H	R
Query Conservation
Alig confidence																																																																						.	.
Template Conservation																																																																						.	.
Template Sequence		N	L	L	A	G	P	S	E	N	D	P	N	L	F	V	A	L	Y	D	F	V	A	S	G	D	N	T	L	S	I	T	K	G	E	K	L	R	V	L	G	Y	N	H	N	G	E	W	C	E	A	Q	T	K	N	G	Q	G	W	V	P	S	N	Y	I	T	P	V	N	.	.	S	L	E	K	H	S	W	Y	H	G
Template Known Secondary structure		T	T	T			G	G	G	S		T	T					S	S		B				S	T	T	B			B		T	T										T	T	S	S							T	T							G	G	G				T	T	.	.	S	G	G	G	S	T	T
Template Predicted Secondary structure																																																																						.	.
Template SS confidence
		72	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.			140	.	.	.	.	.	.	.	.	.
		154	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.		180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.
Predicted Secondary structure																												.
Query SS confidence																												.
Query Sequence		N	I	T	R	N	Q	A	E	H	L	L	R	Q	E	S	K	E	G	A	F	I	V	R	D	S	R	.	H	L	G	S	Y	T	I	S	V	F	M	G	A	R	R	S	T	E	A	A	I	K	H	Y	Q	I	K	K	N	D	S	G	Q	W	Y	V	A	E	R	H	A	F	Q	S	I	P	E	L	I	W	Y	H	Q
Query Conservation																												.
Alig confidence															.													.												.	.	.	.	.	.
Template Conservation															.																									.	.	.	.	.	.
Template Sequence		P	V	S	R	N	A	A	E	Y	L	L	S	S	.	G	I	N	G	S	F	L	V	R	E	S	E	S	S	P	G	Q	R	S	I	S	L	R	Y	.	.	.	.	.	.	E	G	R	V	Y	H	Y	R	I	N	T	A	S	D	G	K	L	Y	V	S	S	E	S	R	F	N	T	L	A	E	L	V	H	H	H	S
Template Known Secondary structure												T	S	S	.	S		T	T								S	S	S	T	T									.	.	.	.	.	.	T	T											T	T	S				S	S	T	T			B	S	S
Template Predicted Secondary structure															.																									.	.	.	.	.	.
Template SS confidence
		150	.	.	.	.	.	.	.	.	.	160	.	.		.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.							.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.
		233	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.		.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.
Predicted Secondary structure																																																														.
Query SS confidence																																																														.
Query Sequence		H	N	A	A	G	L	M	T	R	L	R	Y	P	V	G	L	M	G	S	C	L	P	A	T	A	G	F	S	Y	E	K	W	E	I	D	P	S	E	L	A	F	I	K	E	I	G	S	G	Q	F	G	V	V	H	L	G	E	W	R	S	.	H	I	Q	V	A	I	K	A	I	N	E	G	S	M	S	E	E	D	F
Query Conservation																																																														.
Alig confidence																																																														.
Template Conservation
Template Sequence		T	V	A	D	G	L	I	T	T	L	H	Y	P	A	P	K	R	N	K	P	T	V	Y	G	V	S	P	N	Y	D	K	W	E	M	E	R	T	D	I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	E	G	V	W	K	K	Y	S	L	T	V	A	V	K	T	L	K	E	D	T	M	E	V	E	E	F
Template Known Secondary structure					T	T	S	S	S															S	S	S		S	S	T	T			B			G	G	G							S	G	G	G	T	T	S	S							G	G	G	T										T	T	S
Template Predicted Secondary structure
Template SS confidence
		223	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.
		312	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.		.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390
Predicted Secondary structure																																																	.
Query SS confidence																																																	.
Query Sequence		I	E	E	A	K	V	M	M	K	L	S	H	S	K	L	V	Q	L	Y	G	V	C	I	Q	R	K	P	L	Y	I	V	T	E	F	M	E	N	G	C	L	L	N	Y	L	R	E	N	.	K	G	K	L	R	K	E	M	L	L	S	V	C	Q	D	I	C	E	G	M	E	Y	L	E	R	N	G	Y	I	H	R	D
Query Conservation																																																	.
Alig confidence																																																	.
Template Conservation
Template Sequence		L	K	E	A	A	V	M	K	E	I	K	H	P	N	L	V	Q	L	L	G	V	C	T	R	E	P	P	F	Y	I	I	T	E	F	M	T	Y	G	N	L	L	D	Y	L	R	E	C	N	R	Q	E	V	N	A	V	V	L	L	Y	M	A	T	Q	I	S	S	A	M	E	Y	L	E	K	K	N	F	I	H	R	N
Template Known Secondary structure														T	T	B									S	S	S	S									T	T		B								S		T	T	T	S																						T	T				S
Template Predicted Secondary structure
Template SS confidence
		303	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.
		391	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470
Predicted Secondary structure
Query SS confidence
Query Sequence		L	A	A	R	N	C	L	V	S	S	T	C	I	V	K	I	S	D	F	G	M	T	R	Y	V	L	D	D	E	Y	V	S	S	F	G	A	K	F	P	I	K	W	S	P	P	E	V	F	L	F	N	K	Y	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	V	F	T	E	G	K	M	P	F	E	N	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	A	A	R	N	C	L	V	G	E	N	H	L	V	K	V	A	D	F	G	L	S	R	L	M	T	G	D	T	Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	S	L	A	Y	N	K	F	S	I	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S	P	Y	P	G	I
Template Known Secondary structure			S	G	G	G					G	G	G							T	T						S	S							T	T					G	G	G																													T	T	S			S	S	T	T
Template Predicted Secondary structure
Template SS confidence
		383	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.
		471	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	N	L	Q	V	V	E	A	I	S	E	G	F	R	L	Y	R	P	H	L	A	P	M	S	I	Y	E	V	M	Y	S	C	W	H	E	K	P	E	G	R	P	T	F	A	E	L	L	R	A	V	T	E	I	A	E	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	L	S	Q	V	Y	E	L	L	E	K	D	Y	R	M	E	R	P	E	G	C	P	E	K	V	Y	E	L	M	R	A	C	W	Q	W	N	P	S	D	R	P	S	F	A	E	I	H	Q	A	F	E	T	M	F	Q	E
Template Known Secondary structure												T	T							T	T													T		S	S	G	G	G	S												T	S	S	S	S
Template Predicted Secondary structure
Template SS confidence
		463	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.