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Job DescriptionP16885
Confidence100.00%DateSat Jun 16 10:20:27 BST 2012
Rank3Aligned Residues670
% Identity35%Templatec2fjuB_
PDB info PDB header:signaling protein,apoptosis/hydrolaseChain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: activated rac1 bound to its effector phospholipase c beta 2
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   16...20.........30.........40.........50.........60.........70.........80......
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Query Sequence  SQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSKDFERAK. . . . . . . . .
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Template Sequence  PKVKAYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWTYQSK. EMEFLDITSIRDTRFGKFAKMPKSQKLRDVFNMDF
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SSSSS

TTS
TTS.
GGGGGGS



STTTTS
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   11........20.........30.........40.........50.... .....60.........70.........80.........
 
   87..90.........100.... .....110.........120.........130.........140.........150 .........160...
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Query Sequence  AVRQKEDCCFTILYGTQF. VLSTLSLAADSKEDAVNWLSGLKILHQEAMNASTPTIIESWLRKQI. . YSVDQTRRNSISL
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Template Sequence  PDNSFLLKTLTVVSGPDMVDLTFHNFVSYKENVGKAWAEDVLALVKHPLTANASRS. . TFLDKILVKLKMQLNSEGKIPV
Template Known Secondary structure  TT

GGGT
SSSSS
SSSST
T

..S

TTS
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   90.........100.........110.........120.........130.........140..... ....150.........160.......
 
   164.....170.........180 .........190.. .......200.........210.........220.........230.........240.
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Query Sequence  RELKTILPLINFKVSSA. KFLKDKFVEIGA. HKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAV
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Template Sequence  KNFFQMFPADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSL. . CPRPEIDEIFTSY. . . . . . . . . . . . . . . . M
Template Known Secondary structure  STT
TT


SSS

GGGS
TT..S



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   168.170.........180.........190.........200.........210..... ....220........ .
 
   242.......250.........260.........270.........280.........290.........300.........310.........320.
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Query Sequence  YLHDFQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHY
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Template Sequence  TKEHLTKFINQKQRDQ. . . . . . . . . GLIDKY. EPS. . . . . . GQLSPEGMVWFLCGPENSVLAQDKLLL. HHDMTQPLNHY
Template Known Secondary structure  BTS


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B

STTS
SB
GGGGSS.
S


S
GGG
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   237..240.........250.. ...... .260. ........270.........280........ .290.........
 
   322.......330.........340.........350.........360... ......370.........380.........390.........
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Query Sequence  WISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDG. . PDGKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSF
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Template Sequence  FINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPY
Template Known Secondary structure 
BBSSTTBSS
SSSS
B
TTT




TTTT



TTSS


TTTS

S
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   322.......330.........340.........350.........360.........370.........380.........390.........400.
 
   400......... 410.........420.........430...... ...440.........450.........460.........470....
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Query Sequence  PVILSIEEHC. SVEQQRHMAKAFKEVFGDLLLTKPTEA. . . . SADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDE
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Template Sequence  PIILSFENHVDSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKEESGNLDEEEIKKMQSD
Template Known Secondary structure 




GGGB

S

TTS
SSTT




TTTTTT










TTTTTTTTTT
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   402.......410.........420.........430.........440.........450.........460.........470.........480.
 
   475....480.........490.........500.........510.........520.........530.........540.........550....
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Query Sequence  HKQQGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQDIPPTELHFGEKWFHKKVEKRTSAEKLLQEYCMET
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Template Sequence  EG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TG..............................................................................
Template Predicted Secondary structure 

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   529530
 
   555....560.........570.........580.........590.........600.........610.........620.........630....
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Query Sequence  GGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHLRCAEFELRLTDP
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   635....640.........650.........660.........670.........680.........690.........700.........710....
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Query Sequence  VPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLV
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   715....720.........730.........740.........750.........760.........770.........780.........790....
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Query Sequence  ELVSYYEKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYKAKRSDELSFCRGA
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   795....800.........810.........820.........830.........840.........850.........860.........870....
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Query Sequence  LIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTADFEELEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKSFVF
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   875....880.........890.........900.........910.........920.........930.........940...... ...950..
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Query Sequence  ILEPKQQGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDN. . LENPDF
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRS
Template Known Secondary structure  ............................................GGG





TT
SS





T
T
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   531........540.........550.........560......
 
   953......960.........970.........980.........990.........1000.........1010.........1020.........1030..
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Query Sequence  REIRSFVETKADSIIRQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKYMQMNHALFSLNG
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Template Sequence  YVISSFTELKAYDLLSKASVQFVDYNKRQMSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNG
Template Known Secondary structure  TS

TT
TT





TT


B
TT

STTTGG
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   567..570.........580.........590.........600.........610.........620.........630.........640......
 
   1033......1040.........1050.........1060.........1070.........1080.........1090......... 1100.........1110
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Query Sequence  RTGYVLQPESMRTEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDNNKF. . KTTVVNDNGLS
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Template Sequence  QSGYLLKHEFMRR. . . . . . . . . . . . . . PTTLSITVISGQFLSERS. . . VRTYVEVELFGLPGDPKRRYRTKLSPSTNSIN
Template Known Secondary structure  G
S

GGGT
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SS
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TTS







SSS

SS
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   647..650......... 660.........670....... ..680.........690.........700.........
 
   1111........1120... ......1130.........1140.........1150.........1160.........1170.........1180........
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Query Sequence  PIWAPTQEKVTFE. IYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIELASLLVFCEMRP
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Template Sequence  PVWK. . EEPFVFEKILMPELASLRVAVMEEG. . . . NKFLGHRIIPINALNSGYHHLCLHSESNMPLTMPALFIFLEMKD
Template Known Secondary structure 
B

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S
GGG
TT....TGGGB


TT


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   727..730 .........740.........750..... ....760.........770.........780.........790.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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