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Job DescriptionP16885
Confidence100.00%DateSat Jun 16 10:20:27 BST 2012
Rank4Aligned Residues551
% Identity44%Templatec1djyB_
PDB info PDB header:lipid degradationChain: B: PDB Molecule:phosphoinositide-specific phospholipase c, PDBTitle: phosphoinositide-specific phospholipase c-delta1 from rat2 complexed with inositol-2,4,5-trisphosphate
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   159160.........170.........180.........190.. .......200.........210.........220.........230.......
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Query Sequence  NSISLRELKTILPLINFKVSSAKFLKDKFVEIGA. HKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPD
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Template Sequence  NKMNFKELKDFLKELNIQVDDGY. ARKIFRECDHSQTDSLEDEEIETFYKML. . . . . . . . . . . . TQRAEIDRAFEEAAGS
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TT



.T
SS
SS


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TT
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   158.160.........170.........180 .........190.........200........ .210.........220....
 
   238.240.........250.........260.........270.........280.........290.........300.........310.......
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Query Sequence  ASAVYLHDFQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNP
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Template Sequence  AETLSVERLVTFLQHQQREEEAG. PALALSLIERY. EPSETAKAQRQMTKDGFLMYLLSADGNAFSLAHRRV. YQDMDQP
Template Known Secondary structure  SSSTS

SS
S..


TT
STTTBSB
GGGGS
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S
TTS
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   225....230.........240....... ..250........ .260.........270.........280.........290.... .....300.
 
   318.320.........330.........340.........350.........360.........370.........380.........390.......
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Query Sequence  LSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPDGKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTS
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Template Sequence  LSHYLVSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKAS
Template Known Secondary structure  GGGSSTTBSS
SSS

B
TT



GGG



TTS



TTTS
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   302.......310.........320.........330.........340.........350.........360.........370.........380.
 
   398.400.........410.........420.........430.........440.........450.........460.........470.......
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Query Sequence  SFPVILSIEEHCSVEQQRHMAKAFKEVFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHKQ
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Template Sequence  PYPVILSLENHCSLEQQRVMARHLRAILGPILLDQPLDGVTTSLPSPEQLKGKILLKGKKL. . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  SS


TTSB

S

SS

SS


TTTTTT



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   382.......390.........400.........410.........420.........430.........440..
 
   478.480.........490.........500.........510.........520.........530.........540.........550.......
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Query Sequence  QGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQDIPPTELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGK
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ................................................................................
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   558.560.........570.........580.........590.........600.........610.........620.........630.......
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Query Sequence  DGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHLRCAEFELRLTDPVPN
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Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   638.640.........650.........660.........670.........680.........690.........700.........710.......
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Query Sequence  PNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELV
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Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   718.720.........730.........740.........750.........760.........770.........780.........790.......
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Query Sequence  SYYEKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYKAKRSDELSFCRGALIH
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   798.800.........810.........820.........830.........840.........850.........860.........870.......
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Query Sequence  NVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTADFEELEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKSFVFILE
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   878.880.........890.........900.........910.........920.........930.........940....... ..950....
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Query Sequence  PKQQGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNL. . . ENPDFRE
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GGLDKLKLVPELSDMIIYCKSVHFGGFSSPGTSGQAFYE
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TTT

TT

S






SSS
S

TT
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   443......450.........460.........470.........480.
 
   955....960.........970.........980.........990.........1000.........1010.........1020.........1030....
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Query Sequence  IRSFVETKADSIIRQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKYMQMNHALFSLNGRT
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Template Sequence  MASFSESRALRLLQESGNGFVRHNVSCLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYLGCFQDNGGC
Template Known Secondary structure  S


TT
TT




TTT


TTS
STTSGGG
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   520.........530.........540.........550.........560.........570.........580.........590.........
 
   1035....1040....... ..1050......... 1060.........1070......... 1080.........1090.........1100........
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Query Sequence  GYVLQPESMRTEK. . YDPMPPESQRKI. LMTLTVKVLGARHLPKLGRS. . . IACPFVEVEICGAEYDNNKFKTTVVNDNG
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Template Sequence  GYVLKPAFLRDPNTTFNSRALTQGPWWRPERLRVRIISGQQLPKVNKNKNSIVDPKVIVEIHGVGRDTGSRQTAVITNNG
Template Known Secondary structure  S

GGGS
TT



TTS

SSTT







S

SS



SSGGG




TT
S
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   600.........610.........620.........630.........640.........650.........660.........670.........
 
   11091110.........1120.........1130.........1140.........1150.........1160.........1170.........1180........
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Query Sequence  LSPIWAPTQEKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIELASLLVFCEMRP
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Template Sequence  FNPRW. . . DMEFEFEVTVPDLALVRFMVEDYDSSSKNDFIGQSTIPWNSLKQGYRHVHLLSKNGDQHPSATLFVKISIQD
Template Known Secondary structure  SS
...S
GGG


TTS

GGGB


TTS

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   680.... .....690.........700.........710.........720.........730.........740.........750......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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